KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZHX1
All Species:
17.58
Human Site:
S658
Identified Species:
42.96
UniProt:
Q9UKY1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKY1
NP_001017926.1
873
98098
S658
D
E
S
G
A
P
K
S
G
S
T
G
K
I
C
Chimpanzee
Pan troglodytes
NP_001074953
873
98079
S658
D
E
S
G
A
P
K
S
G
S
T
G
K
I
C
Rhesus Macaque
Macaca mulatta
XP_001100237
873
98006
S658
D
E
S
G
A
P
K
S
G
S
T
G
K
I
C
Dog
Lupus familis
XP_532322
873
98342
P658
D
E
S
G
A
P
K
P
G
N
T
G
K
I
C
Cat
Felis silvestris
Mouse
Mus musculus
P70121
873
97532
S658
D
E
T
V
A
P
K
S
G
G
T
G
K
I
C
Rat
Rattus norvegicus
Q8R515
873
97551
S658
D
E
A
V
A
P
K
S
A
G
T
G
K
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509696
1067
116321
S667
K
K
V
E
E
R
A
S
R
A
E
E
V
E
E
Chicken
Gallus gallus
XP_418454
873
97583
G659
G
A
A
G
S
K
S
G
G
S
G
S
S
K
I
Frog
Xenopus laevis
NP_001085658
925
103577
E674
G
Y
E
D
S
A
D
E
L
I
I
S
E
S
I
Zebra Danio
Brachydanio rerio
XP_001339619
811
90569
Q621
K
A
A
F
V
R
T
Q
W
P
S
S
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
96.2
N.A.
91.2
92.4
N.A.
32.1
81.7
30.3
52
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.4
97.9
N.A.
94.7
94.9
N.A.
47.8
89.5
50.1
65.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
73.3
N.A.
6.6
20
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
20
33.3
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
30
0
60
10
10
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% C
% Asp:
60
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
60
10
10
10
0
0
10
0
0
10
10
20
20
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
50
0
0
0
10
60
20
10
60
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
10
0
0
60
20
% I
% Lys:
20
10
0
0
0
10
60
0
0
0
0
0
60
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
60
0
10
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
20
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
40
0
20
0
10
60
0
40
10
30
10
10
0
% S
% Thr:
0
0
10
0
0
0
10
0
0
0
60
0
0
0
0
% T
% Val:
0
0
10
20
10
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _