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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP50
All Species:
10.3
Human Site:
T259
Identified Species:
18.89
UniProt:
Q9UKX7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKX7
NP_009103.2
468
50144
T259
E
V
A
S
E
K
K
T
D
P
S
S
L
G
A
Chimpanzee
Pan troglodytes
XP_001135221
468
50124
T259
E
V
A
S
E
K
K
T
D
P
S
S
L
G
A
Rhesus Macaque
Macaca mulatta
XP_001109545
468
50114
K259
V
E
V
A
S
E
K
K
T
D
P
S
L
G
A
Dog
Lupus familis
XP_531700
476
50812
K252
A
E
D
A
S
E
K
K
T
D
L
S
V
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIH2
466
49477
S258
E
F
T
A
E
K
K
S
D
A
A
Q
G
A
T
Rat
Rattus norvegicus
O08587
467
49799
S259
E
F
T
A
E
K
K
S
D
A
A
Q
G
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505805
474
48783
G265
T
D
G
P
A
D
T
G
A
E
K
K
E
E
P
Chicken
Gallus gallus
NP_001012559
468
50089
P263
A
A
S
E
K
R
D
P
S
I
G
A
T
S
T
Frog
Xenopus laevis
NP_001089033
436
46689
G250
A
A
P
T
F
N
F
G
Q
K
V
D
S
S
T
Zebra Danio
Brachydanio rerio
NP_963874
421
44559
N235
A
P
P
G
V
S
F
N
F
G
K
K
V
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610355
564
59416
C298
P
L
A
K
K
P
N
C
T
I
T
S
G
G
T
Honey Bee
Apis mellifera
XP_394340
527
58017
S254
K
S
I
F
G
N
I
S
A
G
S
K
S
I
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32499
720
77862
P374
P
S
F
S
F
G
V
P
N
S
S
K
N
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
97
82.5
N.A.
77.9
78.8
N.A.
71
72.2
58.9
53.4
N.A.
32
33.7
N.A.
N.A.
Protein Similarity:
100
99.3
98
87.8
N.A.
86.1
86.9
N.A.
79.1
80.5
71.1
66.8
N.A.
47.7
49.9
N.A.
N.A.
P-Site Identity:
100
100
33.3
26.6
N.A.
33.3
33.3
N.A.
0
0
0
0
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
100
46.6
46.6
N.A.
53.3
53.3
N.A.
0
26.6
6.6
13.3
N.A.
40
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
16
24
31
8
0
0
0
16
16
16
8
0
16
31
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
8
0
31
16
0
8
0
8
0
% D
% Glu:
31
16
0
8
31
16
0
0
0
8
0
0
8
16
0
% E
% Phe:
0
16
8
8
16
0
16
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
8
8
8
8
0
16
0
16
8
0
24
39
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
16
0
0
0
8
0
% I
% Lys:
8
0
0
8
16
31
47
16
0
8
16
31
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
8
0
24
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
8
8
8
0
0
0
8
0
0
% N
% Pro:
16
8
16
8
0
8
0
16
0
16
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
16
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
8
24
16
8
0
24
8
8
31
39
16
16
8
% S
% Thr:
8
0
16
8
0
0
8
16
24
0
8
0
8
0
47
% T
% Val:
8
16
8
0
8
0
8
0
0
0
8
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _