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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAN1B1
All Species:
27.88
Human Site:
S640
Identified Species:
55.76
UniProt:
Q9UKM7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKM7
NP_057303.2
699
79580
S640
V
P
S
G
G
Y
S
S
I
N
N
V
Q
D
P
Chimpanzee
Pan troglodytes
XP_001135997
699
79511
S640
V
P
S
G
G
Y
S
S
I
N
N
V
Q
D
P
Rhesus Macaque
Macaca mulatta
XP_001091256
699
79631
S640
V
P
S
G
G
Y
S
S
I
N
N
V
Q
D
P
Dog
Lupus familis
XP_537786
660
75256
S598
V
P
S
G
G
Y
S
S
I
S
N
V
Q
D
P
Cat
Felis silvestris
Mouse
Mus musculus
P45700
655
73257
L590
V
N
G
G
Y
S
G
L
R
D
V
Y
I
A
R
Rat
Rattus norvegicus
XP_001077558
729
82626
S670
V
P
S
G
G
Y
S
S
I
N
N
V
Q
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415569
675
76361
S616
V
P
T
G
G
Y
T
S
I
N
N
V
Q
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691064
682
77336
S622
V
P
S
G
G
Y
T
S
I
G
N
V
R
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53625
643
72507
Q585
E
P
Q
K
D
D
V
Q
Q
S
F
F
L
A
E
Honey Bee
Apis mellifera
XP_397020
600
68953
R545
Y
T
S
I
G
N
V
R
I
V
Y
N
T
P
Q
Nematode Worm
Caenorhab. elegans
Q18788
590
66931
L535
V
D
S
G
F
T
G
L
Q
N
V
Y
N
P
K
Sea Urchin
Strong. purpuratus
XP_001203783
403
46004
S348
K
I
P
G
G
G
Y
S
S
I
S
N
V
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
75.8
N.A.
32.6
73.6
N.A.
N.A.
66.6
N.A.
60.7
N.A.
30.8
44
29.3
35.9
Protein Similarity:
100
99.7
98.2
82.1
N.A.
50.7
81.8
N.A.
N.A.
79.6
N.A.
73
N.A.
50.7
59
49.9
46.2
P-Site Identity:
100
100
100
93.3
N.A.
13.3
86.6
N.A.
N.A.
80
N.A.
80
N.A.
6.6
20
26.6
20
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
100
N.A.
93.3
N.A.
13.3
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
9
0
0
0
9
0
0
0
42
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
9
9
0
0
0
% F
% Gly:
0
0
9
84
75
9
17
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
67
9
0
0
9
0
0
% I
% Lys:
9
0
0
9
0
0
0
0
0
0
0
0
0
9
9
% K
% Leu:
0
0
0
0
0
0
0
17
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
50
59
17
9
17
9
% N
% Pro:
0
67
9
0
0
0
0
0
0
0
0
0
0
17
50
% P
% Gln:
0
0
9
0
0
0
0
9
17
0
0
0
50
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
0
0
9
0
9
% R
% Ser:
0
0
67
0
0
9
42
67
9
17
9
0
0
0
9
% S
% Thr:
0
9
9
0
0
9
17
0
0
0
0
0
9
0
0
% T
% Val:
75
0
0
0
0
0
17
0
0
9
17
59
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
59
9
0
0
0
9
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _