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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAN1B1
All Species:
26.67
Human Site:
S375
Identified Species:
53.33
UniProt:
Q9UKM7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKM7
NP_057303.2
699
79580
S375
T
P
S
K
I
P
Y
S
D
V
N
I
G
T
G
Chimpanzee
Pan troglodytes
XP_001135997
699
79511
S375
T
P
S
K
I
P
Y
S
D
V
N
I
G
T
G
Rhesus Macaque
Macaca mulatta
XP_001091256
699
79631
S375
T
P
S
K
I
P
Y
S
D
V
N
I
G
T
G
Dog
Lupus familis
XP_537786
660
75256
S333
T
P
S
K
I
P
Y
S
D
V
N
I
G
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P45700
655
73257
A327
T
P
S
G
I
P
W
A
L
L
N
M
K
S
G
Rat
Rattus norvegicus
XP_001077558
729
82626
S405
T
P
S
K
I
P
Y
S
D
V
N
I
G
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415569
675
76361
S351
T
P
S
K
I
P
Y
S
D
V
N
I
G
R
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691064
682
77336
S358
T
P
S
K
I
P
Y
S
D
V
N
I
G
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53625
643
72507
G326
N
Y
G
W
A
S
G
G
S
S
I
L
S
E
F
Honey Bee
Apis mellifera
XP_397020
600
68953
G288
T
A
H
G
P
K
W
G
P
D
S
S
T
S
E
Nematode Worm
Caenorhab. elegans
Q18788
590
66931
K278
S
N
L
D
V
A
S
K
H
A
S
N
Y
G
W
Sea Urchin
Strong. purpuratus
XP_001203783
403
46004
Q91
P
F
S
D
V
N
L
Q
T
G
N
A
H
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
75.8
N.A.
32.6
73.6
N.A.
N.A.
66.6
N.A.
60.7
N.A.
30.8
44
29.3
35.9
Protein Similarity:
100
99.7
98.2
82.1
N.A.
50.7
81.8
N.A.
N.A.
79.6
N.A.
73
N.A.
50.7
59
49.9
46.2
P-Site Identity:
100
100
100
100
N.A.
46.6
100
N.A.
N.A.
93.3
N.A.
93.3
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
80
100
N.A.
N.A.
93.3
N.A.
93.3
N.A.
6.6
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
9
0
9
0
9
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
0
0
59
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
9
17
0
0
9
17
0
9
0
0
59
9
67
% G
% His:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
67
0
0
0
0
0
9
59
0
0
0
% I
% Lys:
0
0
0
59
0
9
0
9
0
0
0
0
9
9
0
% K
% Leu:
0
0
9
0
0
0
9
0
9
9
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
0
0
0
9
0
0
0
0
75
9
0
0
0
% N
% Pro:
9
67
0
0
9
67
0
0
9
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
0
75
0
0
9
9
59
9
9
17
9
9
17
0
% S
% Thr:
75
0
0
0
0
0
0
0
9
0
0
0
9
42
0
% T
% Val:
0
0
0
0
17
0
0
0
0
59
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
9
% W
% Tyr:
0
9
0
0
0
0
59
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _