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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAN1B1
All Species:
9.7
Human Site:
S174
Identified Species:
19.39
UniProt:
Q9UKM7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKM7
NP_057303.2
699
79580
S174
H
L
Q
I
R
P
P
S
Q
D
L
K
D
G
T
Chimpanzee
Pan troglodytes
XP_001135997
699
79511
S174
H
L
Q
I
R
P
P
S
Q
D
L
K
D
G
T
Rhesus Macaque
Macaca mulatta
XP_001091256
699
79631
S174
H
L
Q
I
R
P
P
S
Q
D
L
K
D
G
T
Dog
Lupus familis
XP_537786
660
75256
E136
R
A
P
G
K
D
S
E
D
P
R
Q
G
D
T
Cat
Felis silvestris
Mouse
Mus musculus
P45700
655
73257
A137
H
E
R
A
L
R
E
A
K
E
T
L
Q
K
L
Rat
Rattus norvegicus
XP_001077558
729
82626
N204
H
L
Q
I
R
P
P
N
T
V
S
K
D
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415569
675
76361
W150
N
F
Q
I
K
P
P
W
G
D
V
R
L
Q
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691064
682
77336
L154
S
K
R
G
P
P
A
L
Q
K
R
M
N
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53625
643
72507
S136
S
T
F
S
M
R
S
S
A
G
E
L
T
S
T
Honey Bee
Apis mellifera
XP_397020
600
68953
I99
E
D
I
V
V
D
S
I
N
Q
E
H
K
G
G
Nematode Worm
Caenorhab. elegans
Q18788
590
66931
A89
K
V
E
I
L
R
P
A
R
V
E
S
K
P
P
Sea Urchin
Strong. purpuratus
XP_001203783
403
46004
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
75.8
N.A.
32.6
73.6
N.A.
N.A.
66.6
N.A.
60.7
N.A.
30.8
44
29.3
35.9
Protein Similarity:
100
99.7
98.2
82.1
N.A.
50.7
81.8
N.A.
N.A.
79.6
N.A.
73
N.A.
50.7
59
49.9
46.2
P-Site Identity:
100
100
100
6.6
N.A.
6.6
66.6
N.A.
N.A.
40
N.A.
13.3
N.A.
13.3
6.6
13.3
0
P-Site Similarity:
100
100
100
20
N.A.
33.3
73.3
N.A.
N.A.
66.6
N.A.
33.3
N.A.
13.3
13.3
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
9
17
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
17
0
0
9
34
0
0
34
9
0
% D
% Glu:
9
9
9
0
0
0
9
9
0
9
25
0
0
0
0
% E
% Phe:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
0
9
9
0
0
9
42
9
% G
% His:
42
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
9
50
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
17
0
0
0
9
9
0
34
17
9
0
% K
% Leu:
0
34
0
0
17
0
0
9
0
0
25
17
9
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
9
0
0
0
0
0
0
9
9
0
0
0
9
0
0
% N
% Pro:
0
0
9
0
9
50
50
0
0
9
0
0
0
9
9
% P
% Gln:
0
0
42
0
0
0
0
0
34
9
0
9
9
9
0
% Q
% Arg:
9
0
17
0
34
25
0
0
9
0
17
9
0
0
0
% R
% Ser:
17
0
0
9
0
0
25
34
0
0
9
9
0
9
9
% S
% Thr:
0
9
0
0
0
0
0
0
9
0
9
0
9
0
50
% T
% Val:
0
9
0
9
9
0
0
0
0
17
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _