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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FEM1B
All Species:
26.36
Human Site:
S248
Identified Species:
52.73
UniProt:
Q9UK73
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK73
NP_056137.1
627
70264
S248
H
A
D
C
D
R
R
S
R
I
E
A
L
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083166
564
63568
R220
L
Y
L
A
M
L
E
R
F
Q
D
G
D
N
I
Dog
Lupus familis
XP_535526
720
79995
S341
H
A
D
C
D
R
R
S
R
I
E
A
L
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2G0
627
70205
S248
H
A
D
C
D
R
R
S
R
I
E
A
L
E
L
Rat
Rattus norvegicus
P0C6P7
627
70219
S248
H
A
D
C
D
R
R
S
R
I
E
A
L
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516065
613
68642
S234
H
A
D
C
D
R
A
S
R
I
E
A
L
E
L
Chicken
Gallus gallus
Q5ZM55
627
70376
S248
H
A
G
C
N
R
R
S
R
I
E
A
L
E
L
Frog
Xenopus laevis
Q6GPE5
629
70256
S250
H
S
D
C
D
A
K
S
R
I
E
A
L
E
L
Zebra Danio
Brachydanio rerio
Q7T3P8
618
68460
E243
H
P
Q
T
G
L
A
E
R
I
S
A
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBY1
650
73029
E252
P
E
L
M
S
L
E
E
Q
I
T
A
L
E
L
Honey Bee
Apis mellifera
XP_397133
451
51452
H113
W
C
A
A
G
A
G
H
L
T
I
V
K
I
L
Nematode Worm
Caenorhab. elegans
P17221
656
74268
H249
D
Q
M
P
S
G
I
H
K
R
D
A
L
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.8
86.1
N.A.
99
99.1
N.A.
79.2
90.7
82.8
39.2
N.A.
39
37.6
30.1
N.A.
Protein Similarity:
100
N.A.
89.1
86.5
N.A.
99.8
99.8
N.A.
87.4
96.1
91.5
59.4
N.A.
56
50.8
46.9
N.A.
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
93.3
86.6
80
46.6
N.A.
33.3
6.6
20
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
93.3
93.3
93.3
46.6
N.A.
40
6.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
9
17
0
17
17
0
0
0
0
84
0
0
0
% A
% Cys:
0
9
0
59
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
50
0
50
0
0
0
0
0
17
0
9
0
0
% D
% Glu:
0
9
0
0
0
0
17
17
0
0
59
0
0
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
17
9
9
0
0
0
0
9
0
0
0
% G
% His:
67
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
75
9
0
0
9
9
% I
% Lys:
0
0
0
0
0
0
9
0
9
0
0
0
9
9
0
% K
% Leu:
9
0
17
0
0
25
0
0
9
0
0
0
84
0
92
% L
% Met:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
9
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
0
0
9
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
50
42
9
67
9
0
0
0
0
0
% R
% Ser:
0
9
0
0
17
0
0
59
0
0
9
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
9
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _