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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBR1 All Species: 36.36
Human Site: Y281 Identified Species: 57.14
UniProt: Q9UK59 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK59 NP_057300.2 544 61555 Y281 S A P D Y L E Y D I E W L T I
Chimpanzee Pan troglodytes XP_526319 545 61694 Y281 S A P D Y L E Y D I E W L T I
Rhesus Macaque Macaca mulatta XP_001114637 544 61581 Y281 S A P D Y L E Y D I E W L T I
Dog Lupus familis XP_852077 544 61645 Y281 N A P E Y L E Y D I E W L T V
Cat Felis silvestris
Mouse Mus musculus Q923B1 550 62271 Y281 S A P E Y L E Y D V E W L T V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519946 524 58844 Y250 S A P D Y L E Y D V E W L A I
Chicken Gallus gallus Q5ZLM2 536 60758 Y281 T A G D S L E Y D A E W I A V
Frog Xenopus laevis Q6GPB8 534 61070 Y280 S K P E C L E Y D L E W L A V
Zebra Danio Brachydanio rerio Q7T3E4 568 62871 Y280 G S S E Q L E Y D P E W L A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSD7 534 59444 S275 A A P V P P P S K S V P V T K
Honey Bee Apis mellifera XP_623894 478 54582 A232 A H L H C K F A A L V P E K E
Nematode Worm Caenorhab. elegans Q966M6 500 56663 G251 F E A D H N S G K L G N P S G
Sea Urchin Strong. purpuratus XP_782666 646 72191 Y280 E R P F E L S Y D T E W L A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K01 418 48157 P177 I F L S H D W P V G I T D Y G
Baker's Yeast Sacchar. cerevisiae P24309 405 47723 A164 H V R I S D I A P L F M I K H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.7 90.2 N.A. 85.4 N.A. N.A. 67.6 71.5 64.8 56.5 N.A. 35.6 45.9 35.2 43
Protein Similarity: 100 99.6 99 95.5 N.A. 90.9 N.A. N.A. 77.9 82.5 80.1 70.9 N.A. 51.8 61 53.1 58.6
P-Site Identity: 100 100 100 80 N.A. 80 N.A. N.A. 86.6 53.3 60 53.3 N.A. 20 0 6.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 73.3 80 66.6 N.A. 33.3 13.3 26.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. 41.5 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 54 7 0 0 0 0 14 7 7 0 0 0 34 0 % A
% Cys: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 40 0 14 0 0 67 0 0 0 7 0 0 % D
% Glu: 7 7 0 27 7 0 60 0 0 0 67 0 7 0 7 % E
% Phe: 7 7 0 7 0 0 7 0 0 0 7 0 0 0 0 % F
% Gly: 7 0 7 0 0 0 0 7 0 7 7 0 0 0 14 % G
% His: 7 7 0 7 14 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 7 0 0 7 0 0 7 0 0 27 7 0 14 0 34 % I
% Lys: 0 7 0 0 0 7 0 0 14 0 0 0 0 14 7 % K
% Leu: 0 0 14 0 0 67 0 0 0 27 0 0 60 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 60 0 7 7 7 7 7 7 0 14 7 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 40 7 7 7 14 0 14 7 0 7 0 0 0 7 0 % S
% Thr: 7 0 0 0 0 0 0 0 0 7 0 7 0 40 0 % T
% Val: 0 7 0 7 0 0 0 0 7 14 14 0 7 0 34 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 67 0 0 0 % W
% Tyr: 0 0 0 0 40 0 0 67 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _