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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBR1 All Species: 13.94
Human Site: S455 Identified Species: 21.9
UniProt: Q9UK59 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK59 NP_057300.2 544 61555 S455 N T P S V E P S D Q A S E F S
Chimpanzee Pan troglodytes XP_526319 545 61694 S456 N T P S V E P S D Q A S E F S
Rhesus Macaque Macaca mulatta XP_001114637 544 61581 S456 N T P S V E P S D Q A S E F S
Dog Lupus familis XP_852077 544 61645 S457 T P S A E P S S D Q A S D F S
Cat Felis silvestris
Mouse Mus musculus Q923B1 550 62271 S461 T P S V E P A S D Q A S D L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519946 524 58844 P435 S S V E P A S P D H P P D F S
Chicken Gallus gallus Q5ZLM2 536 60758 P454 D P S P D H P P E F S A S F S
Frog Xenopus laevis Q6GPB8 534 61070 P450 E K L G E P S P E Y T P D L S
Zebra Danio Brachydanio rerio Q7T3E4 568 62871 Q462 D A V V P E G Q V G S Q D S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSD7 534 59444 K447 D R E T K S S K L Q A V E E D
Honey Bee Apis mellifera XP_623894 478 54582 L393 E F K S N E S L M E T S C E Q
Nematode Worm Caenorhab. elegans Q966M6 500 56663 R415 V P P S A Y Y R N P Q S A E F
Sea Urchin Strong. purpuratus XP_782666 646 72191 P506 S P S N Q D F P P S P I K R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K01 418 48157 Q337 V P A Y N P S Q R V F D S I P
Baker's Yeast Sacchar. cerevisiae P24309 405 47723 K324 D T S H A S W K D E N H R M F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.7 90.2 N.A. 85.4 N.A. N.A. 67.6 71.5 64.8 56.5 N.A. 35.6 45.9 35.2 43
Protein Similarity: 100 99.6 99 95.5 N.A. 90.9 N.A. N.A. 77.9 82.5 80.1 70.9 N.A. 51.8 61 53.1 58.6
P-Site Identity: 100 100 100 46.6 N.A. 40 N.A. N.A. 20 20 6.6 6.6 N.A. 20 20 20 0
P-Site Similarity: 100 100 100 60 N.A. 46.6 N.A. N.A. 40 46.6 20 26.6 N.A. 33.3 26.6 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. 41.5 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 14 7 7 0 0 0 40 7 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 27 0 0 0 7 7 0 0 47 0 0 7 34 0 14 % D
% Glu: 14 0 7 7 20 34 0 0 14 14 0 0 27 20 0 % E
% Phe: 0 7 0 0 0 0 7 0 0 7 7 0 0 40 14 % F
% Gly: 0 0 0 7 0 0 7 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 7 0 7 0 0 0 7 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % I
% Lys: 0 7 7 0 7 0 0 14 0 0 0 0 7 0 0 % K
% Leu: 0 0 7 0 0 0 0 7 7 0 0 0 0 14 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % M
% Asn: 20 0 0 7 14 0 0 0 7 0 7 0 0 0 0 % N
% Pro: 0 40 27 7 14 27 27 27 7 7 14 14 0 0 7 % P
% Gln: 0 0 0 0 7 0 0 14 0 40 7 7 0 0 7 % Q
% Arg: 0 7 0 0 0 0 0 7 7 0 0 0 7 7 0 % R
% Ser: 14 7 34 34 0 14 40 34 0 7 14 47 14 7 54 % S
% Thr: 14 27 0 7 0 0 0 0 0 0 14 0 0 0 7 % T
% Val: 14 0 14 14 20 0 0 0 7 7 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 7 7 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _