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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBR1 All Species: 33.33
Human Site: S318 Identified Species: 52.38
UniProt: Q9UK59 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK59 NP_057300.2 544 61555 S318 L H A R W D Y S A T E E G M K
Chimpanzee Pan troglodytes XP_526319 545 61694 S318 L H A R W D Y S A T E E G M K
Rhesus Macaque Macaca mulatta XP_001114637 544 61581 S318 L H A R W D Y S A T E E G M K
Dog Lupus familis XP_852077 544 61645 S318 L H T R W D Y S A T E E A M N
Cat Felis silvestris
Mouse Mus musculus Q923B1 550 62271 S318 L H T R W D Y S A T E E T M K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519946 524 58844 S287 L H T K W D Y S A T E E A M K
Chicken Gallus gallus Q5ZLM2 536 60758 S318 L H A K W D Y S A T E E A I K
Frog Xenopus laevis Q6GPB8 534 61070 S317 L H A R W D F S M S E E T K R
Zebra Danio Brachydanio rerio Q7T3E4 568 62871 S317 L H S R W D F S A S E E A M M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSD7 534 59444 T309 P S D P I E G T P R L E Y D A
Honey Bee Apis mellifera XP_623894 478 54582 H266 L Q V I E I K H N L D L P L K
Nematode Worm Caenorhab. elegans Q966M6 500 56663 K286 F A A L V P H K G S G S G R P
Sea Urchin Strong. purpuratus XP_782666 646 72191 N316 Y C S K W K Y N V N M N Q L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K01 418 48157 A211 T L G S K P A A L L L E K L K
Baker's Yeast Sacchar. cerevisiae P24309 405 47723 K198 T K H L L K L K P F F E Q D I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.7 90.2 N.A. 85.4 N.A. N.A. 67.6 71.5 64.8 56.5 N.A. 35.6 45.9 35.2 43
Protein Similarity: 100 99.6 99 95.5 N.A. 90.9 N.A. N.A. 77.9 82.5 80.1 70.9 N.A. 51.8 61 53.1 58.6
P-Site Identity: 100 100 100 80 N.A. 86.6 N.A. N.A. 80 80 60 66.6 N.A. 6.6 13.3 13.3 13.3
P-Site Similarity: 100 100 100 80 N.A. 86.6 N.A. N.A. 86.6 93.3 80 86.6 N.A. 20 26.6 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. 41.5 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 40 0 0 0 7 7 54 0 0 0 27 0 14 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 60 0 0 0 0 7 0 0 14 0 % D
% Glu: 0 0 0 0 7 7 0 0 0 0 60 80 0 0 0 % E
% Phe: 7 0 0 0 0 0 14 0 0 7 7 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 7 0 7 0 7 0 27 0 0 % G
% His: 0 60 7 0 0 0 7 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 7 7 0 0 0 0 0 0 0 7 7 % I
% Lys: 0 7 0 20 7 14 7 14 0 0 0 0 7 7 54 % K
% Leu: 67 7 0 14 7 0 7 0 7 14 14 7 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 7 0 0 47 7 % M
% Asn: 0 0 0 0 0 0 0 7 7 7 0 7 0 0 7 % N
% Pro: 7 0 0 7 0 14 0 0 14 0 0 0 7 0 7 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 14 0 0 % Q
% Arg: 0 0 0 47 0 0 0 0 0 7 0 0 0 7 7 % R
% Ser: 0 7 14 7 0 0 0 60 0 20 0 7 0 0 0 % S
% Thr: 14 0 20 0 0 0 0 7 0 47 0 0 14 0 0 % T
% Val: 0 0 7 0 7 0 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 54 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _