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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS28
All Species:
35.15
Human Site:
T186
Identified Species:
55.24
UniProt:
Q9UK41
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK41
NP_057292.1
221
25425
T186
T
V
S
Q
W
L
Q
T
L
S
G
M
S
A
S
Chimpanzee
Pan troglodytes
XP_520017
227
25966
S186
T
V
S
Q
W
W
V
S
L
P
A
R
Q
S
P
Rhesus Macaque
Macaca mulatta
XP_001091900
221
25421
T186
T
V
S
Q
W
L
Q
T
L
S
G
M
S
A
S
Dog
Lupus familis
XP_849245
211
24427
T176
T
V
S
Q
W
L
Q
T
L
S
G
M
S
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1C8
221
25434
T186
T
V
S
Q
W
L
Q
T
L
S
G
M
S
A
S
Rat
Rattus norvegicus
B5DEN9
228
26091
T193
T
V
S
Q
W
L
Q
T
L
S
G
M
S
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515562
139
15654
S106
K
F
R
V
S
A
R
S
A
R
E
P
Y
D
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956884
223
25426
T187
K
V
S
L
W
L
T
T
L
S
S
M
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V359
210
24493
S174
K
V
E
K
W
L
G
S
L
N
E
M
Q
A
S
Honey Bee
Apis mellifera
XP_392314
213
24558
T176
K
V
A
E
W
L
Q
T
L
N
N
M
S
A
S
Nematode Worm
Caenorhab. elegans
Q9NA26
210
24203
R172
K
V
K
K
W
H
D
R
L
S
S
M
A
A
S
Sea Urchin
Strong. purpuratus
XP_786883
224
25708
T186
R
I
N
K
W
L
T
T
M
S
S
M
R
A
A
Poplar Tree
Populus trichocarpa
XP_002305661
209
23287
R171
K
M
K
E
W
I
L
R
L
S
K
M
G
A
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S9T7
210
23671
R172
K
M
K
E
W
L
S
R
L
S
K
M
G
A
A
Baker's Yeast
Sacchar. cerevisiae
Q02767
242
27684
R208
K
L
I
D
W
I
V
R
I
N
K
L
S
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
99.5
93.6
N.A.
98.6
95.1
N.A.
47.5
N.A.
N.A.
86.5
N.A.
59.7
67.8
42.9
59.3
Protein Similarity:
100
85.4
100
95.4
N.A.
100
96.9
N.A.
54.7
N.A.
N.A.
93.7
N.A.
77.8
85.5
61.9
80.8
P-Site Identity:
100
40
100
100
N.A.
100
100
N.A.
0
N.A.
N.A.
73.3
N.A.
46.6
66.6
46.6
40
P-Site Similarity:
100
53.3
100
100
N.A.
100
100
N.A.
20
N.A.
N.A.
73.3
N.A.
66.6
86.6
60
73.3
Percent
Protein Identity:
36.6
N.A.
N.A.
38.9
28.5
N.A.
Protein Similarity:
59.7
N.A.
N.A.
59.7
52.8
N.A.
P-Site Identity:
33.3
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
7
0
7
0
7
80
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
7
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
7
20
0
0
0
0
0
0
14
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
34
0
14
0
7
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
14
0
0
7
0
0
0
0
7
0
% I
% Lys:
54
0
20
20
0
0
0
0
0
0
20
0
0
0
0
% K
% Leu:
0
7
0
7
0
67
7
0
80
0
0
7
0
0
0
% L
% Met:
0
14
0
0
0
0
0
0
7
0
0
80
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
20
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
7
% P
% Gln:
0
0
0
40
0
0
40
0
0
0
0
0
14
0
0
% Q
% Arg:
7
0
7
0
0
0
7
27
0
7
0
7
7
0
0
% R
% Ser:
0
0
47
0
7
0
7
20
0
67
20
0
54
7
60
% S
% Thr:
40
0
0
0
0
0
14
54
0
0
0
0
0
0
0
% T
% Val:
0
67
0
7
0
0
14
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
94
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _