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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PURG
All Species:
11.21
Human Site:
S146
Identified Species:
22.42
UniProt:
Q9UJV8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJV8
NP_001015508.1
347
39556
S146
G
H
S
K
E
Q
G
S
R
R
R
Q
K
H
S
Chimpanzee
Pan troglodytes
XP_001136727
295
32969
E111
D
L
A
Q
A
Q
D
E
P
R
R
A
L
K
S
Rhesus Macaque
Macaca mulatta
XP_001085613
304
33781
E120
D
L
A
Q
A
Q
D
E
P
R
R
A
L
K
S
Dog
Lupus familis
XP_539985
347
39520
S146
G
H
G
K
D
Q
A
S
R
R
R
Q
K
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4E6
350
39919
S149
G
Q
S
K
E
Q
V
S
R
R
R
Q
K
H
S
Rat
Rattus norvegicus
Q68A21
315
33399
A121
E
G
G
G
P
R
R
A
L
K
S
E
F
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426295
336
38538
S135
S
N
G
K
E
Q
H
S
R
Q
R
Q
Q
H
P
Frog
Xenopus laevis
Q8AVS4
328
34968
A122
G
P
G
G
P
R
R
A
L
K
S
E
F
L
V
Zebra Danio
Brachydanio rerio
Q6PHK6
297
32588
R113
G
D
D
G
G
P
R
R
A
L
K
S
E
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524624
275
31134
A91
Y
L
A
L
S
T
A
A
E
F
R
D
H
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784262
259
29404
M75
K
S
R
L
T
L
G
M
S
A
A
A
E
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKZ1
296
32182
E112
V
F
Y
F
D
I
G
E
N
R
R
G
R
F
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.1
52.1
97.9
N.A.
96.2
52.1
N.A.
N.A.
78.3
51.8
51.8
N.A.
38.9
N.A.
N.A.
36.6
Protein Similarity:
100
63.4
64.5
99.1
N.A.
97.7
63.6
N.A.
N.A.
84.1
64.2
62.8
N.A.
53
N.A.
N.A.
55.3
P-Site Identity:
100
26.6
26.6
73.3
N.A.
86.6
0
N.A.
N.A.
53.3
6.6
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
40
40
86.6
N.A.
86.6
26.6
N.A.
N.A.
73.3
33.3
20
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
17
0
17
25
9
9
9
25
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
9
0
17
0
17
0
0
0
0
9
0
0
0
% D
% Glu:
9
0
0
0
25
0
0
25
9
0
0
17
17
0
0
% E
% Phe:
0
9
0
9
0
0
0
0
0
9
0
0
17
25
0
% F
% Gly:
42
9
34
25
9
0
25
0
0
0
0
9
0
0
0
% G
% His:
0
17
0
0
0
0
9
0
0
0
0
0
9
34
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
34
0
0
0
0
0
17
9
0
25
17
0
% K
% Leu:
0
25
0
17
0
9
0
0
17
9
0
0
17
25
17
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
17
9
0
0
17
0
0
0
0
0
9
% P
% Gln:
0
9
0
17
0
50
0
0
0
9
0
34
9
0
0
% Q
% Arg:
0
0
9
0
0
17
25
9
34
50
67
0
9
0
9
% R
% Ser:
9
9
17
0
9
0
0
34
9
0
17
9
0
0
42
% S
% Thr:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _