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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEF1
All Species:
28.79
Human Site:
S139
Identified Species:
70.37
UniProt:
Q9UJU2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJU2
NP_001124185.1
399
44201
S139
S
P
P
I
P
R
T
S
N
K
V
P
V
V
Q
Chimpanzee
Pan troglodytes
XP_001136311
414
45726
S139
S
P
P
I
P
R
T
S
N
K
V
P
V
V
Q
Rhesus Macaque
Macaca mulatta
XP_001086645
399
44212
S139
S
P
P
I
P
R
T
S
N
K
V
P
V
V
Q
Dog
Lupus familis
XP_851241
400
44317
S140
S
P
P
I
P
R
T
S
N
K
V
P
V
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P27782
397
44040
S137
S
P
P
I
P
R
T
S
N
K
V
P
V
V
Q
Rat
Rattus norvegicus
Q9QXN1
397
44005
S137
S
P
P
I
P
R
T
S
N
K
V
P
V
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510743
307
34255
L65
E
A
S
A
S
A
S
L
L
T
V
V
L
L
L
Chicken
Gallus gallus
NP_990344
369
40838
G127
N
D
P
Y
M
P
N
G
S
L
S
P
P
I
P
Frog
Xenopus laevis
P70062
554
60282
S154
S
P
S
P
A
H
L
S
N
K
V
P
V
V
Q
Zebra Danio
Brachydanio rerio
Q9YHE8
560
61441
S158
S
P
T
P
G
H
L
S
N
K
V
P
V
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
99.7
98.5
N.A.
97.2
96.2
N.A.
60.1
87.4
43.1
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.9
99.7
99
N.A.
98.5
97.7
N.A.
66.4
89.4
53.7
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
13.3
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
33.3
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
60
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
20
10
10
10
0
0
10
10
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
0
80
0
0
0
0
0
0
% N
% Pro:
0
80
70
20
60
10
0
0
0
0
0
90
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% Q
% Arg:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% R
% Ser:
80
0
20
0
10
0
10
80
10
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
60
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
90
10
80
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _