KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRLS1
All Species:
22.12
Human Site:
T219
Identified Species:
34.76
UniProt:
Q9UJA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA2
NP_001120930.1
301
32593
T219
V
R
Y
R
T
L
P
T
P
R
T
L
A
K
Y
Chimpanzee
Pan troglodytes
XP_001167053
193
20214
M112
N
P
W
T
I
P
N
M
L
S
M
T
R
I
G
Rhesus Macaque
Macaca mulatta
XP_001115876
301
32976
T219
V
R
Y
R
T
L
P
T
P
R
T
L
A
K
Y
Dog
Lupus familis
XP_849915
302
32681
T219
V
R
Y
R
T
L
P
T
P
R
T
L
S
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZM8
303
32484
T220
V
R
Y
R
T
L
P
T
P
R
T
L
A
K
Y
Rat
Rattus norvegicus
Q5U2V5
302
32610
T219
V
R
Y
R
T
L
P
T
P
R
T
L
A
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514453
222
24820
S141
L
S
P
P
R
T
L
S
R
Y
F
N
P
C
Y
Chicken
Gallus gallus
XP_426115
298
32596
P215
V
R
Y
K
T
L
S
P
P
R
T
L
S
R
Y
Frog
Xenopus laevis
NP_001090462
306
34107
P222
V
R
Y
K
T
L
P
P
P
K
T
L
S
R
Y
Zebra Danio
Brachydanio rerio
NP_998096
342
37870
P258
V
R
Y
K
T
V
P
P
P
V
T
L
S
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MZC4
322
36437
P238
I
R
Y
I
S
L
P
P
P
K
T
F
S
R
Y
Honey Bee
Apis mellifera
XP_393196
223
24721
F142
P
K
T
F
A
R
Y
F
N
P
T
Y
A
T
A
Nematode Worm
Caenorhab. elegans
O01916
246
26762
S165
Y
K
R
Y
Q
V
M
S
P
P
Y
S
L
S
R
Sea Urchin
Strong. purpuratus
XP_792193
269
30082
S186
L
R
D
V
G
L
M
S
A
A
F
Y
L
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07560
283
32001
R187
L
K
L
K
Y
P
G
R
V
A
W
N
S
Y
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
89.3
89.4
N.A.
85.8
85
N.A.
64.1
63.4
62
52.9
N.A.
36.3
36.5
36.2
41.2
Protein Similarity:
100
63.7
93
91
N.A.
89.4
89
N.A.
69
71.4
72.8
63.1
N.A.
51.2
53.4
52.1
57.8
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
6.6
66.6
66.6
60
N.A.
46.6
13.3
6.6
20
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
20
86.6
93.3
86.6
N.A.
80
20
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
7
14
0
0
34
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
7
0
0
14
7
0
0
7
% F
% Gly:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
7
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
20
0
27
0
0
0
0
0
14
0
0
0
40
0
% K
% Leu:
20
0
7
0
0
60
7
0
7
0
0
54
14
0
0
% L
% Met:
0
0
0
0
0
0
14
7
0
0
7
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
7
0
7
0
0
14
0
0
0
% N
% Pro:
7
7
7
7
0
14
54
27
67
14
0
0
7
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
7
34
7
7
0
7
7
40
0
0
7
27
7
% R
% Ser:
0
7
0
0
7
0
7
20
0
7
0
7
40
7
0
% S
% Thr:
0
0
7
7
54
7
0
34
0
0
67
7
0
7
0
% T
% Val:
54
0
0
7
0
14
0
0
7
7
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
7
% W
% Tyr:
7
0
60
7
7
0
7
0
0
7
7
14
0
7
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _