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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRLS1 All Species: 16.67
Human Site: S98 Identified Species: 26.19
UniProt: Q9UJA2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJA2 NP_001120930.1 301 32593 S98 G G Q W G P A S T P S L Y E N
Chimpanzee Pan troglodytes XP_001167053 193 20214
Rhesus Macaque Macaca mulatta XP_001115876 301 32976 S98 G G Q W G P A S T P S L Y E N
Dog Lupus familis XP_849915 302 32681 S98 G G R W G Q A S A A S L Y E N
Cat Felis silvestris
Mouse Mus musculus Q80ZM8 303 32484 S99 S A R W V P A S A A S S Y E N
Rat Rattus norvegicus Q5U2V5 302 32610 S98 S A R W V R A S A T S S Y E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514453 222 24820 I26 E Y E N P W T I P N F L S L A
Chicken Gallus gallus XP_426115 298 32596 R94 R E R S A A G R Y A E L Y E N
Frog Xenopus laevis NP_001090462 306 34107 S101 E G D S A Q S S L T H L Y E N
Zebra Danio Brachydanio rerio NP_998096 342 37870 Q137 P A N E G H F Q F K E L Y E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MZC4 322 36437 E117 R V R E K I D E I R E E R E N
Honey Bee Apis mellifera XP_393196 223 24721 F27 N I W T V P N F L C M G R I L
Nematode Worm Caenorhab. elegans O01916 246 26762 K50 L P P E E R G K Y K V A T I P
Sea Urchin Strong. purpuratus XP_792193 269 30082 T63 G A N E F E E T K K K V Q E Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q07560 283 32001 K59 E Y A T N P S K T P H I K S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.7 89.3 89.4 N.A. 85.8 85 N.A. 64.1 63.4 62 52.9 N.A. 36.3 36.5 36.2 41.2
Protein Similarity: 100 63.7 93 91 N.A. 89.4 89 N.A. 69 71.4 72.8 63.1 N.A. 51.2 53.4 52.1 57.8
P-Site Identity: 100 0 100 73.3 N.A. 53.3 46.6 N.A. 6.6 26.6 40 33.3 N.A. 13.3 6.6 0 13.3
P-Site Similarity: 100 0 100 80 N.A. 60 53.3 N.A. 13.3 33.3 46.6 33.3 N.A. 20 6.6 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 27 7 0 14 7 34 0 20 20 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 20 7 7 27 7 7 7 7 0 0 20 7 0 67 0 % E
% Phe: 0 0 0 0 7 0 7 7 7 0 7 0 0 0 0 % F
% Gly: 27 27 0 0 27 0 14 0 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 14 0 0 0 0 % H
% Ile: 0 7 0 0 0 7 0 7 7 0 0 7 0 14 0 % I
% Lys: 0 0 0 0 7 0 0 14 7 20 7 0 7 0 7 % K
% Leu: 7 0 0 0 0 0 0 0 14 0 0 47 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 7 0 14 7 7 0 7 0 0 7 0 0 0 0 60 % N
% Pro: 7 7 7 0 7 34 0 0 7 20 0 0 0 0 7 % P
% Gln: 0 0 14 0 0 14 0 7 0 0 0 0 7 0 7 % Q
% Arg: 14 0 34 0 0 14 0 7 0 7 0 0 14 0 0 % R
% Ser: 14 0 0 14 0 0 14 40 0 0 34 14 7 7 0 % S
% Thr: 0 0 0 14 0 0 7 7 20 14 0 0 7 0 0 % T
% Val: 0 7 0 0 20 0 0 0 0 0 7 7 0 0 0 % V
% Trp: 0 0 7 34 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 14 0 0 0 0 0 0 14 0 0 0 54 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _