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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRLS1
All Species:
30.61
Human Site:
S166
Identified Species:
48.1
UniProt:
Q9UJA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA2
NP_001120930.1
301
32593
S166
N
Q
R
S
A
L
G
S
A
L
D
P
L
A
D
Chimpanzee
Pan troglodytes
XP_001167053
193
20214
R59
R
P
A
A
L
G
L
R
L
P
G
I
G
Q
R
Rhesus Macaque
Macaca mulatta
XP_001115876
301
32976
E166
T
Q
E
G
E
A
R
E
C
L
E
P
G
R
Q
Dog
Lupus familis
XP_849915
302
32681
S166
N
Q
K
S
A
L
G
S
A
L
D
P
L
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZM8
303
32484
S167
N
Q
K
S
A
L
G
S
A
L
D
P
L
A
D
Rat
Rattus norvegicus
Q5U2V5
302
32610
S166
N
Q
K
S
A
L
G
S
A
L
D
P
L
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514453
222
24820
L88
L
G
S
A
L
D
P
L
A
D
K
I
L
I
S
Chicken
Gallus gallus
XP_426115
298
32596
S162
N
Q
K
S
A
L
G
S
A
L
D
P
L
A
D
Frog
Xenopus laevis
NP_001090462
306
34107
S169
N
Q
K
S
A
L
G
S
A
L
D
P
L
A
D
Zebra Danio
Brachydanio rerio
NP_998096
342
37870
S205
N
Q
K
S
A
L
G
S
A
L
D
P
L
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MZC4
322
36437
S185
S
Q
A
S
K
F
G
S
F
L
D
P
M
A
D
Honey Bee
Apis mellifera
XP_393196
223
24721
K89
F
L
D
P
V
A
D
K
L
L
V
G
T
L
F
Nematode Worm
Caenorhab. elegans
O01916
246
26762
G112
P
G
Q
K
S
L
L
G
S
V
L
D
P
V
A
Sea Urchin
Strong. purpuratus
XP_792193
269
30082
A133
D
L
L
D
G
W
I
A
R
N
F
E
N
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07560
283
32001
K134
I
L
D
P
L
A
D
K
L
L
M
I
T
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
89.3
89.4
N.A.
85.8
85
N.A.
64.1
63.4
62
52.9
N.A.
36.3
36.5
36.2
41.2
Protein Similarity:
100
63.7
93
91
N.A.
89.4
89
N.A.
69
71.4
72.8
63.1
N.A.
51.2
53.4
52.1
57.8
P-Site Identity:
100
0
20
93.3
N.A.
93.3
93.3
N.A.
13.3
93.3
93.3
93.3
N.A.
60
6.6
6.6
0
P-Site Similarity:
100
6.6
26.6
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
73.3
6.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
14
47
20
0
7
54
0
0
0
0
54
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
14
7
0
7
14
0
0
7
54
7
0
0
54
% D
% Glu:
0
0
7
0
7
0
0
7
0
0
7
7
0
0
0
% E
% Phe:
7
0
0
0
0
7
0
0
7
0
7
0
0
0
7
% F
% Gly:
0
14
0
7
7
7
54
7
0
0
7
7
14
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
0
20
0
7
0
% I
% Lys:
0
0
40
7
7
0
0
14
0
0
7
0
0
0
0
% K
% Leu:
7
20
7
0
20
54
14
7
20
74
7
0
54
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
47
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% N
% Pro:
7
7
0
14
0
0
7
0
0
7
0
60
7
0
0
% P
% Gln:
0
60
7
0
0
0
0
0
0
0
0
0
0
14
14
% Q
% Arg:
7
0
7
0
0
0
7
7
7
0
0
0
0
7
7
% R
% Ser:
7
0
7
54
7
0
0
54
7
0
0
0
0
0
7
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
14
7
7
% T
% Val:
0
0
0
0
7
0
0
0
0
7
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _