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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
24.85
Human Site:
T534
Identified Species:
42.05
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
T534
G
K
G
Y
F
V
Q
T
P
E
E
L
Q
K
S
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
T534
G
K
G
Y
F
V
Q
T
P
E
E
L
Q
K
S
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
P444
K
G
Y
F
V
K
T
P
E
E
L
Q
K
S
L
Dog
Lupus familis
XP_534256
667
72859
T623
G
K
G
Y
F
V
Q
T
P
E
E
L
Q
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
T537
G
K
G
Y
F
V
R
T
P
E
E
L
Q
H
S
Rat
Rattus norvegicus
Q8CHM7
581
63598
T537
G
K
G
Y
F
V
Q
T
P
E
E
L
Q
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
T524
G
K
G
Y
F
V
N
T
P
E
E
L
Q
N
A
Frog
Xenopus laevis
Q6DDK5
649
71410
F604
S
V
E
D
S
G
A
F
L
V
T
E
K
N
L
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
I578
Y
G
G
K
G
Y
L
I
G
R
E
D
E
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
E524
M
K
G
Y
F
C
T
E
I
E
Q
L
Q
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
S588
R
Y
D
N
V
A
K
S
L
G
S
W
G
E
T
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
E484
F
H
V
T
T
P
A
E
L
E
D
A
L
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
K617
I
P
A
A
R
V
T
K
K
A
D
L
R
E
A
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
T514
A
N
D
F
F
V
N
T
I
S
E
L
S
R
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
6.6
100
N.A.
86.6
93.3
N.A.
N.A.
80
0
13.3
N.A.
46.6
N.A.
0
6.6
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
6.6
20
N.A.
60
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
15
0
0
8
0
8
0
8
22
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
15
8
0
0
0
0
0
0
15
8
0
8
0
% D
% Glu:
0
0
8
0
0
0
0
15
8
65
58
8
8
15
0
% E
% Phe:
8
0
0
15
58
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
43
15
58
0
8
8
0
0
8
8
0
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
8
15
0
0
0
0
0
0
% I
% Lys:
8
50
0
8
0
8
8
8
8
0
0
0
15
22
0
% K
% Leu:
0
0
0
0
0
0
8
0
22
0
8
65
8
0
22
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
15
0
0
0
0
0
0
15
0
% N
% Pro:
0
8
0
0
0
8
0
8
43
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
29
0
0
0
8
8
50
0
8
% Q
% Arg:
8
0
0
0
8
0
8
0
0
8
0
0
8
15
0
% R
% Ser:
8
0
0
0
8
0
0
8
0
8
8
0
8
15
36
% S
% Thr:
0
0
0
8
8
0
22
50
0
0
8
0
0
0
8
% T
% Val:
0
8
8
0
15
58
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
8
8
50
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _