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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
19.39
Human Site:
S541
Identified Species:
32.82
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
S541
T
P
E
E
L
Q
K
S
L
R
Q
S
L
A
D
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
S541
T
P
E
E
L
Q
K
S
L
R
Q
S
L
A
D
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
L451
P
E
E
L
Q
K
S
L
R
Q
S
L
A
D
T
Dog
Lupus familis
XP_534256
667
72859
S630
T
P
E
E
L
Q
K
S
L
R
E
S
L
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
S544
T
P
E
E
L
Q
H
S
L
R
Q
A
L
Q
D
Rat
Rattus norvegicus
Q8CHM7
581
63598
S544
T
P
E
E
L
Q
D
S
L
R
Q
A
L
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
A531
T
P
E
E
L
Q
N
A
V
K
A
S
L
A
D
Frog
Xenopus laevis
Q6DDK5
649
71410
L611
F
L
V
T
E
K
N
L
D
N
L
S
D
Y
M
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
Q585
I
G
R
E
D
E
S
Q
L
E
D
I
I
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
A531
E
I
E
Q
L
Q
A
A
V
K
A
A
N
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
T595
S
L
G
S
W
G
E
T
I
D
E
S
N
A
D
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
L491
E
L
E
D
A
L
R
L
S
L
T
K
H
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
A624
K
K
A
D
L
R
E
A
I
Q
T
M
L
D
T
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
C521
T
I
S
E
L
S
R
C
F
Q
Q
A
V
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
6.6
93.3
N.A.
80
80
N.A.
N.A.
66.6
6.6
13.3
N.A.
20
N.A.
20
13.3
P-Site Similarity:
100
100
20
100
N.A.
86.6
86.6
N.A.
N.A.
86.6
13.3
26.6
N.A.
53.3
N.A.
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
22
0
0
15
29
8
43
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
8
0
8
0
8
8
8
0
8
15
50
% D
% Glu:
15
8
65
58
8
8
15
0
0
8
15
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
8
15
0
0
0
0
0
0
15
0
0
8
8
0
0
% I
% Lys:
8
8
0
0
0
15
22
0
0
15
0
8
0
15
8
% K
% Leu:
0
22
0
8
65
8
0
22
43
8
8
8
50
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
0
0
15
0
0
8
0
0
15
0
8
% N
% Pro:
8
43
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
50
0
8
0
22
36
0
0
22
0
% Q
% Arg:
0
0
8
0
0
8
15
0
8
36
0
0
0
0
0
% R
% Ser:
8
0
8
8
0
8
15
36
8
0
8
43
0
0
0
% S
% Thr:
50
0
0
8
0
0
0
8
0
0
15
0
0
0
15
% T
% Val:
0
0
8
0
0
0
0
0
15
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _