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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM2
All Species:
21.82
Human Site:
S1123
Identified Species:
60
UniProt:
Q9UHN6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHN6
NP_037522.1
1383
154374
S1123
E
R
K
F
Y
F
D
S
S
T
G
L
L
F
L
Chimpanzee
Pan troglodytes
XP_001141007
1383
154353
S1123
E
R
K
F
Y
F
D
S
S
T
G
L
L
F
L
Rhesus Macaque
Macaca mulatta
XP_001091678
1350
150737
I1090
G
L
H
G
L
V
S
I
S
C
R
L
L
F
L
Dog
Lupus familis
XP_541287
1430
159013
S1170
E
R
K
F
Y
F
D
S
S
T
G
L
L
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWI3
1383
153782
S1123
E
R
K
F
Y
F
D
S
G
T
G
L
L
F
L
Rat
Rattus norvegicus
NP_001101066
1371
152726
S1111
E
R
K
F
Y
F
D
S
G
T
G
L
L
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505568
1339
150062
Y1079
E
R
K
F
Y
F
D
Y
S
T
G
L
L
F
L
Chicken
Gallus gallus
XP_413852
1563
171840
R1299
E
Q
L
F
Y
F
D
R
A
L
G
Y
L
F
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KPQ7
1378
152309
K1115
E
R
K
Y
F
F
D
K
S
A
G
L
L
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.5
88.8
N.A.
86.7
86.4
N.A.
76.5
48.2
N.A.
57.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
96.2
93.2
N.A.
92.9
92.5
N.A.
85
61.2
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
33.3
100
N.A.
93.3
93.3
N.A.
93.3
53.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
93.3
93.3
N.A.
93.3
73.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
89
0
0
0
0
0
0
0
0
% D
% Glu:
89
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
78
12
89
0
0
0
0
0
0
0
89
0
% F
% Gly:
12
0
0
12
0
0
0
0
23
0
89
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
78
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
12
12
0
12
0
0
0
0
12
0
89
100
0
89
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
78
0
0
0
0
0
12
0
0
12
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
12
56
67
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
12
78
0
0
12
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _