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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG2
All Species:
21.52
Human Site:
S275
Identified Species:
52.59
UniProt:
Q9UHN1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHN1
NP_009146.2
485
54911
S275
M
S
P
S
N
F
S
S
S
D
C
Q
D
E
E
Chimpanzee
Pan troglodytes
XP_001162210
485
54788
S275
M
S
P
S
N
F
S
S
S
D
C
Q
D
E
E
Rhesus Macaque
Macaca mulatta
XP_001109823
373
41508
L186
G
K
L
R
E
N
L
L
H
G
A
L
E
H
Y
Dog
Lupus familis
XP_548032
485
54395
S275
V
S
P
S
N
F
S
S
S
D
C
Q
D
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZM2
459
51414
S249
M
S
P
S
N
F
S
S
A
D
C
Q
D
E
L
Rat
Rattus norvegicus
NP_001100530
459
51619
S249
V
S
P
S
N
F
S
S
V
D
C
Q
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510804
427
47331
E240
Y
N
F
P
W
G
K
E
S
V
E
A
L
W
N
Chicken
Gallus gallus
XP_415670
464
51598
S254
V
G
P
S
N
F
S
S
S
D
F
Q
D
E
E
Frog
Xenopus laevis
Q9W6G7
463
52265
C253
Q
S
P
S
G
F
S
C
N
D
I
Q
D
G
Q
Zebra Danio
Brachydanio rerio
XP_001922359
442
50570
Y250
S
H
G
V
K
V
L
Y
N
F
P
W
G
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
68.6
86.5
N.A.
73.4
73.4
N.A.
58.3
58.5
49.9
43.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
71.7
92.3
N.A.
82.8
83
N.A.
69.9
70.9
67.2
64.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
86.6
73.3
N.A.
6.6
80
53.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
93.3
80
N.A.
13.3
86.6
66.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
50
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
70
0
0
70
0
0
% D
% Glu:
0
0
0
0
10
0
0
10
0
0
10
0
10
50
50
% E
% Phe:
0
0
10
0
0
70
0
0
0
10
10
0
0
0
0
% F
% Gly:
10
10
10
0
10
10
0
0
0
10
0
0
10
20
0
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
20
10
0
0
0
10
10
0
10
% L
% Met:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
60
10
0
0
20
0
0
0
0
0
10
% N
% Pro:
0
0
70
10
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
70
0
0
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
60
0
70
0
0
70
60
50
0
0
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
30
0
0
10
0
10
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _