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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT9 All Species: 3.64
Human Site: S247 Identified Species: 10
UniProt: Q9UHD8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHD8 NP_001106963.1 586 65401 S247 E A T E A A P S C V G D M A D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102088 360 40906 R54 D T I I E Q M R K K T M K T G
Dog Lupus familis XP_540458 602 66902 G259 E A P E A A P G C I G D M A D
Cat Felis silvestris
Mouse Mus musculus Q80UG5 583 65556 S245 E D S E V T P S C V G D M A D
Rat Rattus norvegicus Q9QZR6 564 63773 A244 R D A M L K Q A P V S R N E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505764 436 49083 D129 D F G Y V G I D A I L E Q M R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGU8 361 40623 G55 S A L L G Y I G I D T I I E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795119 662 73144 G327 D Y N I M V V G V V Q F S E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25342 322 37006 D16 P A S Y V G F D T I T N Q I E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 42.4 85.5 N.A. 90 85.8 N.A. 60.5 N.A. N.A. 41.1 N.A. N.A. N.A. N.A. 37.7
Protein Similarity: 100 N.A. 50.6 89.3 N.A. 94 89.7 N.A. 66.7 N.A. N.A. 50.6 N.A. N.A. N.A. N.A. 53.9
P-Site Identity: 100 N.A. 0 80 N.A. 73.3 6.6 N.A. 0 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 6.6 86.6 N.A. 80 13.3 N.A. 20 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 45 12 0 23 23 0 12 12 0 0 0 0 34 0 % A
% Cys: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % C
% Asp: 34 23 0 0 0 0 0 23 0 12 0 34 0 0 34 % D
% Glu: 34 0 0 34 12 0 0 0 0 0 0 12 0 34 12 % E
% Phe: 0 12 0 0 0 0 12 0 0 0 0 12 0 0 12 % F
% Gly: 0 0 12 0 12 23 0 34 0 0 34 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 23 0 0 23 0 12 34 0 12 12 12 0 % I
% Lys: 0 0 0 0 0 12 0 0 12 12 0 0 12 0 12 % K
% Leu: 0 0 12 12 12 0 0 0 0 0 12 0 0 0 0 % L
% Met: 0 0 0 12 12 0 12 0 0 0 0 12 34 12 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 12 12 0 0 % N
% Pro: 12 0 12 0 0 0 34 0 12 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 12 0 0 0 12 0 23 0 12 % Q
% Arg: 12 0 0 0 0 0 0 12 0 0 0 12 0 0 12 % R
% Ser: 12 0 23 0 0 0 0 23 0 0 12 0 12 0 0 % S
% Thr: 0 12 12 0 0 12 0 0 12 0 34 0 0 12 0 % T
% Val: 0 0 0 0 34 12 12 0 12 45 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 23 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _