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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC63
All Species:
30.3
Human Site:
S576
Identified Species:
51.28
UniProt:
Q9UGP8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGP8
NP_009145.1
760
87997
S576
V
S
D
K
G
S
D
S
E
E
E
E
T
N
R
Chimpanzee
Pan troglodytes
XP_001148185
760
87976
S576
V
S
D
K
G
S
D
S
E
E
E
E
T
N
R
Rhesus Macaque
Macaca mulatta
XP_001091991
689
79874
K530
T
A
K
S
K
K
K
K
P
L
K
K
K
P
T
Dog
Lupus familis
XP_532252
850
96553
S666
V
S
D
K
G
S
D
S
E
E
E
E
T
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHE0
760
87823
S576
I
S
D
K
G
S
D
S
E
E
E
E
T
N
R
Rat
Rattus norvegicus
NP_001101107
727
83574
E565
S
E
A
A
M
K
E
E
E
E
D
I
S
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511532
775
89598
S591
L
S
D
K
G
S
D
S
E
E
E
E
A
N
R
Chicken
Gallus gallus
XP_419802
759
87965
S575
I
S
D
K
G
S
E
S
E
E
E
E
T
N
R
Frog
Xenopus laevis
NP_001088542
754
87189
S574
G
S
D
K
G
S
D
S
E
D
E
D
Q
N
R
Zebra Danio
Brachydanio rerio
XP_002666271
754
86861
S573
L
S
D
K
G
S
E
S
D
E
A
E
G
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648111
753
85835
D577
E
S
E
A
G
N
A
D
G
S
D
V
E
S
A
Honey Bee
Apis mellifera
XP_395961
751
87148
K569
T
N
T
P
N
A
K
K
K
E
D
K
I
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793617
800
91710
E577
V
M
A
V
K
L
S
E
Y
A
K
P
L
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14906
663
75326
F505
P
Y
S
F
A
P
F
F
P
T
K
R
R
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
89.3
88.3
N.A.
96.1
91.8
N.A.
86.8
91.5
83.4
72.3
N.A.
44
42.3
N.A.
40.8
Protein Similarity:
100
99.8
89.8
89.1
N.A.
98.5
94.2
N.A.
91.8
95.7
91.8
84.7
N.A.
63.6
62.3
N.A.
59
P-Site Identity:
100
100
0
100
N.A.
93.3
13.3
N.A.
86.6
86.6
73.3
60
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
100
20
100
N.A.
100
46.6
N.A.
93.3
100
86.6
86.6
N.A.
40
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
15
8
8
8
0
0
8
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
58
0
0
0
43
8
8
8
22
8
0
8
0
% D
% Glu:
8
8
8
0
0
0
22
15
58
65
50
50
8
8
0
% E
% Phe:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
65
0
0
0
8
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
0
0
8
58
15
15
15
15
8
0
22
15
8
0
22
% K
% Leu:
15
0
0
0
0
8
0
0
0
8
0
0
8
8
0
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
8
0
0
0
0
0
0
0
58
0
% N
% Pro:
8
0
0
8
0
8
0
0
15
0
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
58
% R
% Ser:
8
65
8
8
0
58
8
58
0
8
0
0
8
8
8
% S
% Thr:
15
0
8
0
0
0
0
0
0
8
0
0
36
0
8
% T
% Val:
29
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _