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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC63
All Species:
39.39
Human Site:
S459
Identified Species:
66.67
UniProt:
Q9UGP8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGP8
NP_009145.1
760
87997
S459
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Chimpanzee
Pan troglodytes
XP_001148185
760
87976
S459
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Rhesus Macaque
Macaca mulatta
XP_001091991
689
79874
H425
S
D
R
H
T
L
L
H
F
L
E
D
E
K
Y
Dog
Lupus familis
XP_532252
850
96553
S549
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHE0
760
87823
S459
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Rat
Rattus norvegicus
NP_001101107
727
83574
S459
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511532
775
89598
S474
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Chicken
Gallus gallus
XP_419802
759
87965
S459
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Frog
Xenopus laevis
NP_001088542
754
87189
S459
H
V
L
D
D
E
D
S
N
K
I
T
V
G
S
Zebra Danio
Brachydanio rerio
XP_002666271
754
86861
S458
Q
V
L
D
D
E
D
S
N
N
I
T
A
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648111
753
85835
T458
E
V
I
D
D
E
N
T
N
V
V
T
A
G
A
Honey Bee
Apis mellifera
XP_395961
751
87148
P463
E
V
I
D
D
E
N
P
T
V
Y
T
A
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793617
800
91710
K447
E
V
V
D
D
D
D
K
A
T
I
T
A
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14906
663
75326
D400
G
K
L
F
T
L
E
D
A
K
I
G
E
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
89.3
88.3
N.A.
96.1
91.8
N.A.
86.8
91.5
83.4
72.3
N.A.
44
42.3
N.A.
40.8
Protein Similarity:
100
99.8
89.8
89.1
N.A.
98.5
94.2
N.A.
91.8
95.7
91.8
84.7
N.A.
63.6
62.3
N.A.
59
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
100
86.6
93.3
N.A.
46.6
40
N.A.
46.6
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
100
100
86.6
93.3
N.A.
86.6
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
0
29
0
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
86
86
8
72
8
0
0
0
8
0
0
0
% D
% Glu:
22
0
0
0
0
79
8
0
0
0
8
0
15
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
8
0
86
0
% G
% His:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
79
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
8
0
15
0
0
0
8
0
% K
% Leu:
0
0
72
0
0
15
8
0
0
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
72
58
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
65
0
0
0
0
0
0
65
% S
% Thr:
0
0
0
0
15
0
0
8
8
8
0
86
0
0
0
% T
% Val:
0
86
8
0
0
0
0
0
0
15
8
0
58
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _