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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
32.12
Human Site:
Y571
Identified Species:
58.89
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
Y571
P
N
Q
V
R
M
R
Y
L
L
K
V
Q
F
N
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
G519
K
H
S
T
K
G
L
G
K
M
A
P
S
S
A
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
Y571
P
N
Q
V
R
M
R
Y
L
L
K
V
Q
F
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
Y547
P
N
Q
V
R
M
R
Y
L
L
K
I
Q
F
N
Rat
Rattus norvegicus
P27008
1014
112642
K1004
V
N
L
K
Y
L
L
K
L
K
F
N
F
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
K1001
V
N
L
K
Y
L
L
K
L
K
F
N
Y
K
T
Frog
Xenopus laevis
P31669
998
111108
K987
V
N
L
K
Y
L
L
K
L
K
F
N
Y
K
G
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
Y635
P
A
Q
I
Q
M
K
Y
L
L
R
V
Q
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
Y984
V
A
Q
V
N
I
Q
Y
L
F
R
M
E
F
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
Y933
V
D
Q
I
Q
L
K
Y
L
V
R
V
K
M
H
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
Y727
T
N
Q
I
R
M
R
Y
L
V
K
L
K
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
Y642
V
D
Q
I
R
M
R
Y
V
L
H
V
N
F
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
Y627
V
E
Q
I
K
M
R
Y
V
I
Q
V
K
F
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
0
100
N.A.
N.A.
93.3
13.3
N.A.
N.A.
13.3
13.3
66.6
N.A.
33.3
N.A.
26.6
66.6
P-Site Similarity:
100
20
100
N.A.
N.A.
100
20
N.A.
N.A.
20
20
93.3
N.A.
66.6
N.A.
86.6
93.3
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
60
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
80
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
24
0
8
62
0
% F
% Gly:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
0
0
0
39
0
8
0
0
0
8
0
8
0
0
0
% I
% Lys:
8
0
0
24
16
0
16
24
8
24
31
0
24
24
8
% K
% Leu:
0
0
24
0
0
31
31
0
77
39
0
8
0
0
0
% L
% Met:
0
0
0
0
0
54
0
0
0
8
0
8
0
8
0
% M
% Asn:
0
54
0
0
8
0
0
0
0
0
0
24
8
0
54
% N
% Pro:
31
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
70
0
16
0
8
0
0
0
8
0
31
0
0
% Q
% Arg:
0
0
0
0
39
0
47
0
0
0
24
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% S
% Thr:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
16
% T
% Val:
54
0
0
31
0
0
0
0
16
16
0
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
24
0
0
70
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _