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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
31.52
Human Site:
Y556
Identified Species:
57.78
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
Y556
P
D
G
Y
T
L
N
Y
N
E
Y
I
V
Y
N
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
K504
E
L
L
E
A
N
P
K
A
E
G
L
L
Q
G
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
Y556
P
D
G
Y
T
L
N
Y
N
E
Y
I
V
Y
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
Y532
P
E
G
Y
T
L
N
Y
N
E
F
I
V
Y
S
Rat
Rattus norvegicus
P27008
1014
112642
Y989
T
C
L
L
Y
N
E
Y
I
V
Y
D
I
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
Y986
T
C
L
L
Y
N
E
Y
I
V
Y
D
V
A
Q
Frog
Xenopus laevis
P31669
998
111108
Y972
T
S
L
L
Y
N
E
Y
I
V
Y
D
I
A
Q
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
Y620
K
G
G
Y
S
L
L
Y
N
E
Y
I
V
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
Y969
H
L
K
S
S
L
L
Y
N
E
Y
I
V
Y
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
Y918
D
V
D
Y
H
L
L
Y
N
E
F
I
V
Y
D
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
Y712
P
N
G
Y
T
L
N
Y
N
E
Y
V
V
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
Y627
S
K
R
G
G
L
L
Y
N
E
Y
I
V
Y
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
Y612
C
S
K
G
M
L
L
Y
N
E
Y
I
V
Y
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
6.6
100
N.A.
N.A.
80
13.3
N.A.
N.A.
20
13.3
73.3
N.A.
53.3
N.A.
53.3
86.6
P-Site Similarity:
100
20
100
N.A.
N.A.
100
20
N.A.
N.A.
20
20
80
N.A.
66.6
N.A.
66.6
100
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
60
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
0
24
0
% A
% Cys:
8
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
8
0
0
0
0
0
0
0
0
24
0
0
16
% D
% Glu:
8
8
0
8
0
0
24
0
0
77
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% F
% Gly:
0
8
39
16
8
0
0
0
0
0
8
0
0
0
8
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
24
0
0
62
16
0
0
% I
% Lys:
8
8
16
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
16
31
24
0
70
39
0
0
0
0
8
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
31
31
0
70
0
0
0
0
0
47
% N
% Pro:
31
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
24
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
0
8
16
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
24
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
24
0
8
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
47
24
0
0
93
0
0
77
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _