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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
11.21
Human Site:
T62
Identified Species:
20.56
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
T62
G
K
A
N
K
D
R
T
E
D
K
Q
D
G
M
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
T62
G
K
A
N
K
D
R
T
E
D
K
Q
D
G
M
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
T62
G
N
A
N
E
D
R
T
E
D
K
Q
D
G
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
S62
R
T
K
D
N
R
D
S
V
K
T
L
L
L
K
Rat
Rattus norvegicus
P27008
1014
112642
K255
N
I
K
D
E
L
K
K
A
C
S
T
N
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
I265
N
D
L
K
E
L
L
I
A
N
K
Q
E
V
P
Frog
Xenopus laevis
P31669
998
111108
K240
H
I
K
D
E
L
K
K
V
C
S
T
N
D
L
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
N131
P
V
S
K
K
R
R
N
E
G
R
S
Q
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
I417
G
G
K
F
E
V
K
I
S
E
N
T
I
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
A251
N
P
D
E
N
D
F
A
K
K
R
R
M
K
K
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
E214
N
E
P
K
V
E
E
E
E
E
M
E
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
I118
N
G
G
K
K
D
V
I
Q
R
L
L
S
A
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
T89
I
K
R
G
L
D
T
T
G
T
K
K
D
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
100
80
N.A.
N.A.
0
0
N.A.
N.A.
13.3
0
20
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
86.6
N.A.
N.A.
13.3
33.3
N.A.
N.A.
33.3
33.3
33.3
N.A.
33.3
N.A.
26.6
40
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
0
0
8
16
0
0
0
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% C
% Asp:
0
8
8
24
0
47
8
0
0
24
0
0
31
16
0
% D
% Glu:
0
8
0
8
39
8
8
8
39
16
0
8
16
8
8
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
31
16
8
8
0
0
0
0
8
8
0
0
0
24
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
0
0
0
0
24
0
0
0
0
8
0
8
% I
% Lys:
0
24
31
31
31
0
24
16
8
16
39
8
0
16
16
% K
% Leu:
0
0
8
0
8
24
8
0
0
0
8
16
8
16
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
16
% M
% Asn:
39
8
0
24
16
0
0
8
0
8
8
0
16
0
0
% N
% Pro:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
31
8
0
0
% Q
% Arg:
8
0
8
0
0
16
31
0
0
8
16
8
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
8
8
0
16
8
8
0
0
% S
% Thr:
0
8
0
0
0
0
8
31
0
8
8
24
0
0
16
% T
% Val:
0
8
0
0
8
8
8
0
16
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _