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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARP2 All Species: 11.21
Human Site: T62 Identified Species: 20.56
UniProt: Q9UGN5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGN5 NP_001036083.1 583 66206 T62 G K A N K D R T E D K Q D G M
Chimpanzee Pan troglodytes XP_001137329 531 60196 T62 G K A N K D R T E D K Q D G M
Rhesus Macaque Macaca mulatta XP_001088314 583 66217 T62 G N A N E D R T E D K Q D G T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88554 559 63378 S62 R T K D N R D S V K T L L L K
Rat Rattus norvegicus P27008 1014 112642 K255 N I K D E L K K A C S T N D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P26446 1011 113502 I265 N D L K E L L I A N K Q E V P
Frog Xenopus laevis P31669 998 111108 K240 H I K D E L K K V C S T N D L
Zebra Danio Brachydanio rerio XP_001923129 647 72923 N131 P V S K K R R N E G R S Q K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35875 994 113773 I417 G G K F E V K I S E N T I A I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4H4 945 107988 A251 N P D E N D F A K K R R M K K
Sea Urchin Strong. purpuratus XP_001199118 736 83866 E214 N E P K V E E E E E M E E E E
Poplar Tree Populus trichocarpa
Maize Zea mays O50017 653 72977 I118 N G G K K D V I Q R L L S A T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q11207 637 72157 T89 I K R G L D T T G T K K D L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.9 97.4 N.A. N.A. 84.2 27.1 N.A. N.A. 27.9 25.7 55.6 N.A. 26.6 N.A. 23.8 42.5
Protein Similarity: 100 91 98.4 N.A. N.A. 90.7 40.2 N.A. N.A. 40.9 41 70.9 N.A. 40.8 N.A. 38.7 56.2
P-Site Identity: 100 100 80 N.A. N.A. 0 0 N.A. N.A. 13.3 0 20 N.A. 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 86.6 N.A. N.A. 13.3 33.3 N.A. N.A. 33.3 33.3 33.3 N.A. 33.3 N.A. 26.6 40
Percent
Protein Identity: N.A. 42.5 N.A. 41.6 N.A. N.A.
Protein Similarity: N.A. 56.8 N.A. 57.6 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 24 0 0 0 0 8 16 0 0 0 0 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % C
% Asp: 0 8 8 24 0 47 8 0 0 24 0 0 31 16 0 % D
% Glu: 0 8 0 8 39 8 8 8 39 16 0 8 16 8 8 % E
% Phe: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 31 16 8 8 0 0 0 0 8 8 0 0 0 24 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 16 0 0 0 0 0 24 0 0 0 0 8 0 8 % I
% Lys: 0 24 31 31 31 0 24 16 8 16 39 8 0 16 16 % K
% Leu: 0 0 8 0 8 24 8 0 0 0 8 16 8 16 24 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 16 % M
% Asn: 39 8 0 24 16 0 0 8 0 8 8 0 16 0 0 % N
% Pro: 8 8 8 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 31 8 0 0 % Q
% Arg: 8 0 8 0 0 16 31 0 0 8 16 8 0 0 0 % R
% Ser: 0 0 8 0 0 0 0 8 8 0 16 8 8 0 0 % S
% Thr: 0 8 0 0 0 0 8 31 0 8 8 24 0 0 16 % T
% Val: 0 8 0 0 8 8 8 0 16 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _