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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
17.58
Human Site:
T530
Identified Species:
32.22
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
T530
P
S
S
A
H
F
V
T
L
N
G
S
T
V
P
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
R478
A
N
Y
C
F
A
S
R
L
K
N
T
G
L
L
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
T530
P
S
S
A
H
F
V
T
L
N
G
S
T
V
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
T506
P
S
P
A
H
F
I
T
L
N
G
S
T
V
P
Rat
Rattus norvegicus
P27008
1014
112642
T963
P
D
P
S
A
S
I
T
L
D
G
V
E
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
T960
P
D
P
T
A
T
T
T
L
D
G
V
E
V
P
Frog
Xenopus laevis
P31669
998
111108
Q946
P
D
P
S
A
T
V
Q
L
D
G
V
D
V
P
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
S594
P
D
P
K
K
S
V
S
L
N
G
V
T
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
S943
T
M
P
D
P
T
K
S
Y
I
R
S
D
G
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
P892
E
I
G
S
Y
N
H
P
D
G
Y
T
I
P
L
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
M686
D
P
K
K
N
F
T
M
D
D
G
T
I
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
S601
T
A
P
N
M
V
E
S
K
V
A
D
D
G
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
A586
T
A
P
N
P
S
E
A
Q
T
L
E
D
G
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
6.6
100
N.A.
N.A.
86.6
40
N.A.
N.A.
40
40
53.3
N.A.
6.6
N.A.
0
26.6
P-Site Similarity:
100
26.6
100
N.A.
N.A.
93.3
60
N.A.
N.A.
46.6
53.3
60
N.A.
13.3
N.A.
20
46.6
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
24
24
8
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
31
0
8
0
0
0
0
16
31
0
8
31
0
0
% D
% Glu:
8
0
0
0
0
0
16
0
0
0
0
8
16
0
0
% E
% Phe:
0
0
0
0
8
31
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
8
62
0
8
24
0
% G
% His:
0
0
0
0
24
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
16
0
0
8
0
0
16
0
0
% I
% Lys:
0
0
8
16
8
0
8
0
8
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
62
0
8
0
0
8
16
% L
% Met:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
16
8
8
0
0
0
31
8
0
0
0
0
% N
% Pro:
54
8
62
0
16
0
0
8
0
0
0
0
0
8
62
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% R
% Ser:
0
24
16
24
0
24
8
24
0
0
0
31
0
0
0
% S
% Thr:
24
0
0
8
0
24
16
39
0
8
0
24
31
0
0
% T
% Val:
0
0
0
0
0
8
31
0
0
8
0
31
0
62
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _