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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARP2 All Species: 33.94
Human Site: T271 Identified Species: 62.22
UniProt: Q9UGN5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGN5 NP_001036083.1 583 66206 T271 K A P L G K L T V A Q I K A G
Chimpanzee Pan troglodytes XP_001137329 531 60196 N261 M M M E M K Y N T K K A P L G
Rhesus Macaque Macaca mulatta XP_001088314 583 66217 T271 K A P L G K L T V A Q I K A G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88554 559 63378 S257 Q I K A G Y Q S L K K I E D C
Rat Rattus norvegicus P27008 1014 112642 S702 K M P L G K L S R R Q I Q A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P26446 1011 113502 S699 K M P L G K L S K R Q I Q S A
Frog Xenopus laevis P31669 998 111108 S685 K M P L G K L S K R Q I Q S A
Zebra Danio Brachydanio rerio XP_001923129 647 72923 T335 K A P L G K L T A E Q I R A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35875 994 113773 S684 K M P L G K L S A H Q I Q S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4H4 945 107988 S626 K M P L G R L S H N Q I N L A
Sea Urchin Strong. purpuratus XP_001199118 736 83866 T429 K A P L G K L T V D Q I K A G
Poplar Tree Populus trichocarpa
Maize Zea mays O50017 653 72977 R341 K L P L G K L R K A T I L K G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q11207 637 72157 S326 K L P L G K I S K S T I S K G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.9 97.4 N.A. N.A. 84.2 27.1 N.A. N.A. 27.9 25.7 55.6 N.A. 26.6 N.A. 23.8 42.5
Protein Similarity: 100 91 98.4 N.A. N.A. 90.7 40.2 N.A. N.A. 40.9 41 70.9 N.A. 40.8 N.A. 38.7 56.2
P-Site Identity: 100 13.3 100 N.A. N.A. 13.3 60 N.A. N.A. 53.3 53.3 80 N.A. 53.3 N.A. 46.6 93.3
P-Site Similarity: 100 20 100 N.A. N.A. 46.6 73.3 N.A. N.A. 73.3 73.3 86.6 N.A. 73.3 N.A. 60 93.3
Percent
Protein Identity: N.A. 42.5 N.A. 41.6 N.A. N.A.
Protein Similarity: N.A. 56.8 N.A. 57.6 N.A. N.A.
P-Site Identity: N.A. 60 N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. 60 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 31 0 8 0 0 0 0 16 24 0 8 0 39 39 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 93 0 0 0 0 0 0 0 0 0 54 % G
% His: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 0 0 0 93 0 0 0 % I
% Lys: 85 0 8 0 0 85 0 0 31 16 16 0 24 16 0 % K
% Leu: 0 16 0 85 0 0 77 0 8 0 0 0 8 16 0 % L
% Met: 8 47 8 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 0 0 8 0 0 % N
% Pro: 0 0 85 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 70 0 31 0 0 % Q
% Arg: 0 0 0 0 0 8 0 8 8 24 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 54 0 8 0 0 8 24 0 % S
% Thr: 0 0 0 0 0 0 0 31 8 0 16 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _