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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
14.85
Human Site:
S8
Identified Species:
27.22
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
S8
M
A
A
R
R
R
R
S
T
G
G
G
R
A
R
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
S8
M
A
A
R
R
R
R
S
T
G
G
G
R
A
R
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
S8
M
A
A
R
R
R
R
S
T
R
G
G
R
A
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
S8
M
A
P
R
R
Q
R
S
G
S
G
R
R
V
L
Rat
Rattus norvegicus
P27008
1014
112642
A201
A
L
K
K
Q
L
P
A
V
K
S
E
G
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
E211
T
E
G
K
R
K
G
E
E
V
D
G
N
V
V
Frog
Xenopus laevis
P31669
998
111108
P186
D
S
L
K
K
K
L
P
A
V
K
N
E
G
K
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
T77
V
K
M
T
Q
T
N
T
V
S
K
Y
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
L363
K
S
T
F
S
R
S
L
L
K
T
N
K
N
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
S197
A
L
A
A
K
R
R
S
T
E
P
A
T
P
A
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
N160
L
N
D
M
E
Q
C
N
D
E
T
D
V
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
N64
V
A
V
D
G
K
R
N
C
G
N
N
K
R
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
A35
L
V
E
R
L
E
E
A
I
A
E
D
T
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
100
93.3
N.A.
N.A.
53.3
6.6
N.A.
N.A.
13.3
0
0
N.A.
6.6
N.A.
33.3
6.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
60
26.6
N.A.
N.A.
26.6
33.3
33.3
N.A.
20
N.A.
40
26.6
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
39
31
8
0
0
0
16
8
8
0
8
0
24
8
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
0
0
8
0
8
16
0
0
0
% D
% Glu:
0
8
8
0
8
8
8
8
8
16
8
8
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
8
0
8
24
31
31
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
8
8
24
16
24
0
0
0
16
16
0
24
16
31
% K
% Leu:
16
16
8
0
8
8
8
8
8
0
0
0
0
0
8
% L
% Met:
31
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
16
0
0
8
24
8
8
8
% N
% Pro:
0
0
8
0
0
0
8
8
0
0
8
0
0
8
0
% P
% Gln:
0
0
0
0
16
16
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
39
39
39
47
0
0
8
0
8
31
16
39
% R
% Ser:
0
16
0
0
8
0
8
39
0
16
8
0
0
0
0
% S
% Thr:
8
0
8
8
0
8
0
8
31
0
16
0
16
0
0
% T
% Val:
16
8
8
0
0
0
0
0
16
16
0
0
8
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _