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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
44.85
Human Site:
S430
Identified Species:
82.22
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
S430
R
M
L
L
W
H
G
S
R
M
S
N
W
V
G
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
T389
I
S
Q
Y
L
Q
S
T
H
A
P
T
H
S
D
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
S430
R
M
L
L
W
H
G
S
R
L
S
N
W
V
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
S406
R
M
L
L
W
H
G
S
R
L
S
N
W
V
G
Rat
Rattus norvegicus
P27008
1014
112642
S864
R
R
L
L
W
H
G
S
R
T
T
N
F
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
S861
R
Q
L
L
W
H
G
S
R
T
T
N
F
A
G
Frog
Xenopus laevis
P31669
998
111108
S847
R
Q
L
L
W
H
G
S
R
T
T
N
F
A
G
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
S494
R
M
L
L
W
H
G
S
R
L
S
N
W
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
S846
R
K
L
L
W
H
G
S
R
L
T
N
F
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
S790
R
R
L
L
W
H
G
S
G
K
M
N
F
A
G
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
S585
R
M
L
L
W
H
G
S
R
M
T
N
W
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
S503
R
M
L
L
W
H
G
S
R
L
S
N
W
A
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
S488
R
M
L
L
W
H
G
S
R
L
T
N
W
A
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
0
93.3
N.A.
N.A.
93.3
66.6
N.A.
N.A.
66.6
66.6
93.3
N.A.
73.3
N.A.
60
86.6
P-Site Similarity:
100
6.6
100
N.A.
N.A.
100
80
N.A.
N.A.
80
80
100
N.A.
93.3
N.A.
66.6
93.3
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
86.6
N.A.
80
N.A.
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
93.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% F
% Gly:
0
0
0
0
0
0
93
0
8
0
0
0
0
0
93
% G
% His:
0
0
0
0
0
93
0
0
8
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
93
93
8
0
0
0
0
47
0
0
0
0
0
% L
% Met:
0
54
0
0
0
0
0
0
0
16
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
16
8
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
93
16
0
0
0
0
0
0
85
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
93
0
0
39
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
24
47
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% V
% Trp:
0
0
0
0
93
0
0
0
0
0
0
0
54
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _