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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
32.73
Human Site:
S376
Identified Species:
60
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
S376
L
R
P
L
D
H
E
S
Y
E
F
K
V
I
S
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
E350
A
I
K
L
V
K
T
E
L
Q
S
P
E
H
P
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
S376
L
R
P
L
D
H
E
S
Y
E
F
K
V
I
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
S352
L
R
P
L
D
H
E
S
N
E
F
K
V
I
S
Rat
Rattus norvegicus
P27008
1014
112642
S808
I
K
V
V
D
R
D
S
E
E
A
E
V
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
S805
I
K
V
V
D
K
D
S
E
E
A
K
I
I
K
Frog
Xenopus laevis
P31669
998
111108
S791
I
K
V
V
A
K
D
S
E
E
S
R
I
I
C
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
S440
L
Q
P
L
D
T
D
S
N
E
Y
K
V
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
S790
L
V
A
L
D
K
N
S
E
E
F
S
I
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
C737
M
E
P
L
Q
Q
G
C
D
D
W
N
M
I
H
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
S534
M
K
P
I
D
K
T
S
E
T
F
K
V
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
S447
F
T
P
L
E
A
D
S
D
E
Y
S
M
I
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
S432
L
T
P
V
G
N
D
S
E
E
F
S
M
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
6.6
100
N.A.
N.A.
93.3
33.3
N.A.
N.A.
33.3
20
60
N.A.
46.6
N.A.
20
40
P-Site Similarity:
100
13.3
100
N.A.
N.A.
93.3
66.6
N.A.
N.A.
66.6
60
80
N.A.
60
N.A.
46.6
60
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
0
0
0
16
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% C
% Asp:
0
0
0
0
62
0
47
0
16
8
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
24
8
47
77
0
8
8
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
24
0
0
0
0
0
0
0
8
8
% H
% Ile:
24
8
0
8
0
0
0
0
0
0
0
0
24
70
8
% I
% Lys:
0
31
8
0
0
39
0
0
0
0
0
47
0
0
16
% K
% Leu:
47
0
0
62
0
0
0
0
8
0
0
0
0
8
0
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
16
0
0
8
0
0
0
% N
% Pro:
0
0
62
0
0
0
0
0
0
0
0
8
0
0
8
% P
% Gln:
0
8
0
0
8
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
24
0
0
0
8
0
0
0
0
0
8
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
85
0
0
16
24
0
0
31
% S
% Thr:
0
16
0
0
0
8
16
0
0
8
0
0
0
0
0
% T
% Val:
0
8
24
31
8
0
0
0
0
0
0
0
47
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
16
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _