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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
10.3
Human Site:
S353
Identified Species:
18.89
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
S353
L
V
K
T
E
L
Q
S
P
E
H
P
L
D
Q
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
L327
L
I
R
T
Q
K
E
L
S
E
K
I
Q
L
L
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
S353
L
V
K
T
E
L
Q
S
P
E
H
P
L
D
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
G329
L
V
K
S
E
R
Q
G
L
E
H
P
L
D
Q
Rat
Rattus norvegicus
P27008
1014
112642
S785
L
R
G
G
S
D
D
S
S
K
D
P
I
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
G782
L
R
G
G
N
E
D
G
D
K
D
P
I
D
I
Frog
Xenopus laevis
P31669
998
111108
G768
L
R
G
G
A
D
D
G
E
K
D
P
I
D
V
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
S417
M
V
Q
S
N
V
K
S
D
E
H
P
L
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
D767
I
K
S
E
D
V
S
D
A
C
N
P
L
D
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
L714
D
V
P
A
S
T
S
L
G
I
D
P
V
D
I
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
E511
V
L
K
S
E
K
N
E
D
E
H
P
I
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
D424
L
L
E
D
D
S
S
D
Q
D
D
P
L
Y
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
L409
L
L
S
V
D
P
G
L
Q
D
D
P
L
Y
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
20
100
N.A.
N.A.
73.3
26.6
N.A.
N.A.
20
20
46.6
N.A.
20
N.A.
20
46.6
P-Site Similarity:
100
46.6
100
N.A.
N.A.
80
40
N.A.
N.A.
33.3
33.3
86.6
N.A.
46.6
N.A.
26.6
73.3
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
8
24
16
24
16
24
16
47
0
0
77
0
% D
% Glu:
0
0
8
8
31
8
8
8
8
47
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
24
24
0
0
8
24
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
8
0
8
31
0
16
% I
% Lys:
0
8
31
0
0
16
8
0
0
24
8
0
0
0
0
% K
% Leu:
70
24
0
0
0
16
0
24
8
0
0
0
54
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
8
0
0
0
8
0
0
0
8
% N
% Pro:
0
0
8
0
0
8
0
0
16
0
0
93
0
0
0
% P
% Gln:
0
0
8
0
8
0
24
0
16
0
0
0
8
0
31
% Q
% Arg:
0
24
8
0
0
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
16
24
16
8
24
31
16
0
0
0
0
0
0
% S
% Thr:
0
0
0
24
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
8
39
0
8
0
16
0
0
0
0
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _