KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PISD
All Species:
36.97
Human Site:
Y162
Identified Species:
67.78
UniProt:
Q9UG56
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UG56
NP_055153.1
408
46573
Y162
A
V
E
D
L
H
H
Y
R
N
L
S
E
F
F
Chimpanzee
Pan troglodytes
XP_515087
419
47798
Y172
A
V
E
D
L
H
H
Y
R
N
L
S
E
F
F
Rhesus Macaque
Macaca mulatta
XP_001111773
409
46891
Y162
A
V
E
D
L
H
H
Y
R
N
L
S
E
F
F
Dog
Lupus familis
XP_534739
409
46776
Y162
A
V
E
D
L
H
H
Y
R
N
L
S
E
F
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSF4
406
45908
Y159
A
V
E
D
L
H
H
Y
R
N
L
S
E
F
F
Rat
Rattus norvegicus
XP_002725046
409
45994
Y162
A
V
E
D
L
Q
H
Y
R
N
L
S
E
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515601
373
42661
C145
K
P
Q
A
R
P
V
C
G
V
H
S
V
I
S
Chicken
Gallus gallus
XP_415253
409
46521
Y162
A
V
E
D
L
H
H
Y
R
N
L
S
E
F
F
Frog
Xenopus laevis
NP_001087912
411
47318
Y169
A
V
E
D
L
H
Q
Y
R
N
L
S
E
F
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651208
447
50470
Y191
M
Y
P
E
Y
E
H
Y
N
S
L
A
E
F
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10949
377
42469
D144
M
Y
D
C
R
M
D
D
C
V
D
P
D
F
K
Sea Urchin
Strong. purpuratus
XP_001180823
382
43384
H147
V
R
P
V
D
A
H
H
M
L
V
S
P
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39006
500
56576
Y180
E
D
P
D
L
T
H
Y
A
N
L
S
E
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
96.8
91.1
N.A.
84.5
84.5
N.A.
73
79.2
64.2
N.A.
N.A.
39.3
N.A.
34
48.7
Protein Similarity:
100
78.5
97.3
94.1
N.A.
89.2
89.2
N.A.
79.1
86.3
72.9
N.A.
N.A.
52.7
N.A.
50.7
60.5
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
6.6
100
93.3
N.A.
N.A.
40
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
13.3
100
93.3
N.A.
N.A.
60
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
0
0
8
0
8
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
8
8
0
0
0
0
8
0
% C
% Asp:
0
8
8
70
8
0
8
8
0
0
8
0
8
0
8
% D
% Glu:
8
0
62
8
0
8
0
0
0
0
0
0
77
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
85
77
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
54
77
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
70
0
0
0
0
8
77
0
0
0
0
% L
% Met:
16
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
70
0
0
0
0
0
% N
% Pro:
0
8
24
0
0
8
0
0
0
0
0
8
8
0
0
% P
% Gln:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
16
0
0
0
62
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
85
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
8
62
0
8
0
0
8
0
0
16
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
8
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _