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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PISD
All Species:
23.03
Human Site:
T224
Identified Species:
42.22
UniProt:
Q9UG56
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UG56
NP_055153.1
408
46573
T224
F
L
G
P
R
M
C
T
E
D
L
P
F
P
P
Chimpanzee
Pan troglodytes
XP_515087
419
47798
T235
F
L
G
P
R
T
C
T
E
D
L
P
F
P
P
Rhesus Macaque
Macaca mulatta
XP_001111773
409
46891
T225
F
L
G
P
R
T
Y
T
E
D
L
P
F
P
P
Dog
Lupus familis
XP_534739
409
46776
T225
F
L
G
P
R
T
S
T
D
D
L
P
F
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSF4
406
45908
T222
F
L
G
P
R
A
N
T
E
D
L
P
F
P
P
Rat
Rattus norvegicus
XP_002725046
409
45994
T225
F
L
G
P
R
A
C
T
E
D
L
P
F
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515601
373
42661
Q196
V
D
D
V
S
F
S
Q
A
T
S
C
S
S
F
Chicken
Gallus gallus
XP_415253
409
46521
T225
F
L
G
P
R
I
S
T
E
D
F
R
F
S
E
Frog
Xenopus laevis
NP_001087912
411
47318
G227
Y
S
L
E
S
F
L
G
P
Q
T
W
T
E
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651208
447
50470
L251
I
E
D
F
L
G
P
L
E
T
V
E
Q
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10949
377
42469
E196
K
V
E
D
N
K
I
E
Y
V
K
G
H
D
Y
Sea Urchin
Strong. purpuratus
XP_001180823
382
43384
D199
P
F
H
P
G
F
F
D
Q
V
S
D
E
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39006
500
56576
N306
F
K
P
S
V
S
K
N
I
H
L
L
S
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
96.8
91.1
N.A.
84.5
84.5
N.A.
73
79.2
64.2
N.A.
N.A.
39.3
N.A.
34
48.7
Protein Similarity:
100
78.5
97.3
94.1
N.A.
89.2
89.2
N.A.
79.1
86.3
72.9
N.A.
N.A.
52.7
N.A.
50.7
60.5
P-Site Identity:
100
93.3
86.6
73.3
N.A.
86.6
93.3
N.A.
0
60
0
N.A.
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
93.3
86.6
80
N.A.
86.6
93.3
N.A.
0
66.6
6.6
N.A.
N.A.
13.3
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
0
8
0
0
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
24
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
16
8
0
0
0
8
8
54
0
8
0
16
0
% D
% Glu:
0
8
8
8
0
0
0
8
54
0
0
8
8
8
8
% E
% Phe:
62
8
0
8
0
24
8
0
0
0
8
0
54
0
8
% F
% Gly:
0
0
54
0
8
8
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
0
8
8
0
0
0
8
0
0
0
0
% K
% Leu:
0
54
8
0
8
0
8
8
0
0
54
8
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
16
% N
% Pro:
8
0
8
62
0
0
8
0
8
0
0
47
0
39
47
% P
% Gln:
0
0
0
0
0
0
0
8
8
8
0
0
8
8
0
% Q
% Arg:
0
0
0
0
54
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
8
0
8
16
8
24
0
0
0
16
0
16
16
0
% S
% Thr:
0
0
0
0
0
24
0
54
0
16
8
0
8
0
0
% T
% Val:
8
8
0
8
8
0
0
0
0
16
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _