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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PISD
All Species:
12.73
Human Site:
S22
Identified Species:
23.33
UniProt:
Q9UG56
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UG56
NP_055153.1
408
46573
S22
G
V
A
P
W
R
S
S
L
H
P
C
E
I
T
Chimpanzee
Pan troglodytes
XP_515087
419
47798
K35
P
R
S
R
G
G
G
K
G
T
G
G
Q
P
P
Rhesus Macaque
Macaca mulatta
XP_001111773
409
46891
S22
G
V
A
P
W
R
S
S
L
H
H
R
E
I
T
Dog
Lupus familis
XP_534739
409
46776
S22
G
V
T
P
W
R
S
S
L
L
H
C
E
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSF4
406
45908
S22
G
G
V
L
W
R
S
S
P
C
H
Y
E
S
T
Rat
Rattus norvegicus
XP_002725046
409
45994
S22
E
G
V
L
W
R
S
S
P
C
H
C
D
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515601
373
42661
P21
A
G
K
W
L
Q
F
P
Q
L
A
L
R
R
R
Chicken
Gallus gallus
XP_415253
409
46521
C22
R
S
S
F
L
T
G
C
N
F
L
I
R
E
N
Frog
Xenopus laevis
NP_001087912
411
47318
K26
K
V
K
L
H
V
R
K
T
R
S
A
T
A
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651208
447
50470
S58
A
R
H
L
R
Q
F
S
S
N
P
A
S
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10949
377
42469
K20
M
L
P
A
V
S
K
K
V
V
S
P
P
M
M
Sea Urchin
Strong. purpuratus
XP_001180823
382
43384
Q21
L
S
I
F
L
T
V
Q
I
R
V
P
D
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39006
500
56576
F44
A
V
L
W
N
R
K
F
S
T
R
L
F
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
96.8
91.1
N.A.
84.5
84.5
N.A.
73
79.2
64.2
N.A.
N.A.
39.3
N.A.
34
48.7
Protein Similarity:
100
78.5
97.3
94.1
N.A.
89.2
89.2
N.A.
79.1
86.3
72.9
N.A.
N.A.
52.7
N.A.
50.7
60.5
P-Site Identity:
100
0
86.6
73.3
N.A.
46.6
40
N.A.
0
0
6.6
N.A.
N.A.
13.3
N.A.
0
0
P-Site Similarity:
100
13.3
86.6
73.3
N.A.
46.6
46.6
N.A.
6.6
6.6
13.3
N.A.
N.A.
26.6
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
16
8
0
0
0
0
0
0
8
16
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
16
0
24
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
31
8
8
% E
% Phe:
0
0
0
16
0
0
16
8
0
8
0
0
8
0
0
% F
% Gly:
31
24
0
0
8
8
16
0
8
0
8
8
0
0
0
% G
% His:
0
0
8
0
8
0
0
0
0
16
31
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
8
0
16
0
% I
% Lys:
8
0
16
0
0
0
16
24
0
0
0
0
0
8
0
% K
% Leu:
8
8
8
31
24
0
0
0
24
16
8
16
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
8
0
0
0
8
8
0
0
0
8
8
% N
% Pro:
8
0
8
24
0
0
0
8
16
0
16
16
8
8
8
% P
% Gln:
0
0
0
0
0
16
0
8
8
0
0
0
8
0
8
% Q
% Arg:
8
16
0
8
8
47
8
0
0
16
8
8
16
8
8
% R
% Ser:
0
16
16
0
0
8
39
47
16
0
16
0
8
16
8
% S
% Thr:
0
0
8
0
0
16
0
0
8
16
0
0
8
0
39
% T
% Val:
0
39
16
0
8
8
8
0
8
8
8
0
0
8
0
% V
% Trp:
0
0
0
16
39
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _