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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APEX2
All Species:
18.18
Human Site:
T200
Identified Species:
50
UniProt:
Q9UBZ4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBZ4
NP_055296.2
518
57401
T200
I
I
L
G
D
L
N
T
A
H
R
P
I
D
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092143
518
57312
T200
I
I
L
G
D
L
N
T
A
H
R
P
I
D
H
Dog
Lupus familis
XP_548620
487
54088
V183
P
I
D
H
W
D
A
V
N
L
E
C
F
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q68G58
516
57321
T199
I
I
L
G
D
L
N
T
A
H
R
P
I
D
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510545
549
60839
T209
I
I
L
G
D
V
N
T
S
H
R
P
I
D
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086779
517
57708
T186
I
I
L
G
D
V
N
T
S
H
R
P
L
D
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784420
596
66588
A188
V
I
V
G
D
V
N
A
S
H
R
R
I
D
H
Poplar Tree
Populus trichocarpa
XP_002304326
617
69328
I192
F
V
V
G
D
L
N
I
A
P
T
A
M
D
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38207
520
59427
R208
K
V
L
L
R
R
V
R
N
L
D
K
I
G
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
81.4
N.A.
79.5
N.A.
N.A.
48
N.A.
52.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
Protein Similarity:
100
N.A.
98.4
87.2
N.A.
86.2
N.A.
N.A.
63.3
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
55.3
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
N.A.
N.A.
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
41.9
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
40
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
12
45
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
12
0
78
12
0
0
0
0
12
0
0
78
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
12
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
78
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
12
0
0
0
0
0
67
0
0
0
0
67
% H
% Ile:
56
78
0
0
0
0
0
12
0
0
0
0
67
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% K
% Leu:
0
0
67
12
0
45
0
0
0
23
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
78
0
23
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
12
0
56
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
12
0
12
0
0
67
12
0
0
12
% R
% Ser:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
56
0
0
12
0
0
0
0
% T
% Val:
12
23
23
0
0
34
12
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _