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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APEX2
All Species:
8.18
Human Site:
T149
Identified Species:
22.5
UniProt:
Q9UBZ4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBZ4
NP_055296.2
518
57401
T149
T
W
E
G
K
E
K
T
L
T
L
I
N
V
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092143
518
57312
I149
T
W
E
G
K
E
R
I
L
T
L
I
N
V
Y
Dog
Lupus familis
XP_548620
487
54088
K136
C
P
H
A
D
A
G
K
P
E
R
L
T
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q68G58
516
57321
T148
T
L
E
G
K
E
K
T
L
T
L
I
N
V
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510545
549
60839
T158
T
S
D
K
R
E
K
T
L
T
V
I
N
V
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086779
517
57708
V138
D
K
E
E
T
L
T
V
I
N
V
Y
C
P
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784420
596
66588
D137
K
K
D
G
A
L
G
D
L
V
I
I
N
V
Y
Poplar Tree
Populus trichocarpa
XP_002304326
617
69328
F142
V
V
T
D
H
N
H
F
V
L
F
N
L
Y
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38207
520
59427
E159
L
D
E
K
S
A
L
E
L
D
S
E
G
R
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
81.4
N.A.
79.5
N.A.
N.A.
48
N.A.
52.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
Protein Similarity:
100
N.A.
98.4
87.2
N.A.
86.2
N.A.
N.A.
63.3
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
55.3
P-Site Identity:
100
N.A.
86.6
0
N.A.
93.3
N.A.
N.A.
66.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
N.A.
93.3
6.6
N.A.
93.3
N.A.
N.A.
86.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
41.9
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
23
0
0
0
0
0
0
0
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% C
% Asp:
12
12
23
12
12
0
0
12
0
12
0
0
0
0
0
% D
% Glu:
0
0
56
12
0
45
0
12
0
12
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
12
0
0
12
0
% F
% Gly:
0
0
0
45
0
0
23
0
0
0
0
0
12
0
12
% G
% His:
0
0
12
0
12
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
12
0
12
56
0
0
0
% I
% Lys:
12
23
0
23
34
0
34
12
0
0
0
0
0
0
12
% K
% Leu:
12
12
0
0
0
23
12
0
67
12
34
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
12
0
12
56
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
12
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
12
0
0
0
12
0
0
12
12
% R
% Ser:
0
12
0
0
12
0
0
0
0
0
12
0
0
0
0
% S
% Thr:
45
0
12
0
12
0
12
34
0
45
0
0
12
0
0
% T
% Val:
12
12
0
0
0
0
0
12
12
12
23
0
0
56
0
% V
% Trp:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
56
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _