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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A2 All Species: 23.94
Human Site: Y537 Identified Species: 43.89
UniProt: Q9UBY0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBY0 NP_003039.2 812 91520 Y537 F K K F D D K Y L R K L L I R
Chimpanzee Pan troglodytes XP_525838 812 91515 Y537 F K K F D D K Y L R K L L I R
Rhesus Macaque Macaca mulatta XP_001108368 812 91659 Y537 F K K F D D K Y L R K L L I R
Dog Lupus familis XP_531775 801 90567 Y526 F K K F D D K Y L R K L L I R
Cat Felis silvestris
Mouse Mus musculus Q8BUE1 797 90919 F524 V R D K F K K F D H R Y L R K
Rat Rattus norvegicus P48763 813 91384 Y538 F K K F D D K Y L R K L L I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514675 940 104115 Y665 F K K F D D K Y L R R L L I R
Chicken Gallus gallus Q5ZJ75 574 64115 Y303 I I F A Y L P Y G L A E G I S
Frog Xenopus laevis NP_001081553 781 87800 S504 S I N E E I H S E F L D H L L
Zebra Danio Brachydanio rerio NP_001107567 746 85353 M474 S H Y R W K D M F M K F N N R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P35449 667 75263 G396 Q F I M S Y G G L R G A I A Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 V264 N L E C C L F V L F P Y F S Y
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 L362 E N F I F I Y L G L E L F T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 96.5 87.1 N.A. 52.9 90.9 N.A. 71.6 21.7 44.8 45.2 N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: 100 99.7 97.6 90.7 N.A. 68.7 94.2 N.A. 77.5 38.9 62.5 63.5 N.A. N.A. N.A. 53.6 N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 100 N.A. 93.3 13.3 0 13.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 40 100 N.A. 100 13.3 13.3 13.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.6 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 8 8 0 8 0 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 47 47 8 0 8 0 0 8 0 0 0 % D
% Glu: 8 0 8 8 8 0 0 0 8 0 8 8 0 0 8 % E
% Phe: 47 8 16 47 16 0 8 8 8 16 0 8 16 0 0 % F
% Gly: 0 0 0 0 0 0 8 8 16 0 8 0 8 0 0 % G
% His: 0 8 0 0 0 0 8 0 0 8 0 0 8 0 0 % H
% Ile: 8 16 8 8 0 16 0 0 0 0 0 0 8 54 0 % I
% Lys: 0 47 47 8 0 16 54 0 0 0 47 0 0 0 8 % K
% Leu: 0 8 0 0 0 16 0 8 62 16 8 54 54 8 8 % L
% Met: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 0 % M
% Asn: 8 8 8 0 0 0 0 0 0 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 8 0 0 0 0 0 54 16 0 0 8 54 % R
% Ser: 16 0 0 0 8 0 0 8 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 8 8 54 0 0 0 16 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _