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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTSF All Species: 10.61
Human Site: S380 Identified Species: 21.21
UniProt: Q9UBX1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBX1 NP_003784.2 484 53366 S380 A K V Y I N D S V E L S Q N E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533219 442 49089 L341 Y I N D S M E L S Q N E Q K L
Cat Felis silvestris
Mouse Mus musculus Q9R013 462 51642 S358 A K V Y I N D S V E L S R N E
Rat Rattus norvegicus P07154 334 37642 K233 V D I P Q Q E K A L M K A V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001071036 473 52706 S369 V A A Y I N S S V E L P K D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN93 614 68942 F503 S H V Q V A G F V D L P K G N
Honey Bee Apis mellifera XP_392381 802 91371 A692 A K V Q V V G A V N I T S N E
Nematode Worm Caenorhab. elegans NP_505215 477 55198 S373 I A V Y I N G S V E L P H D E
Sea Urchin Strong. purpuratus XP_791714 494 55214 F382 A L M M Q F Y F G G I A H P W
Poplar Tree Populus trichocarpa XP_002316398 327 35821 I226 I A V D E N Q I A A N L V H H
Maize Zea mays Q10716 371 40329 I270 A Q I S A N L I K H G P L A I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43296 368 40400 N267 D E E Q I A A N L V K N G P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77 N.A. 75.2 28.9 N.A. N.A. N.A. N.A. 47.5 N.A. 33.5 28.9 37.5 33.6
Protein Similarity: 100 N.A. N.A. 84.3 N.A. 85.1 43.1 N.A. N.A. N.A. N.A. 64 N.A. 47 40.9 53.3 51.6
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 93.3 0 N.A. N.A. N.A. N.A. 53.3 N.A. 20 40 60 6.6
P-Site Similarity: 100 N.A. N.A. 20 N.A. 100 20 N.A. N.A. N.A. N.A. 66.6 N.A. 46.6 66.6 66.6 26.6
Percent
Protein Identity: 31.8 32.6 N.A. 33 N.A. N.A.
Protein Similarity: 44 44.8 N.A. 46.6 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 26.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 25 9 0 9 17 9 9 17 9 0 9 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 17 0 0 17 0 0 9 0 0 0 17 0 % D
% Glu: 0 9 9 0 9 0 17 0 0 34 0 9 0 0 42 % E
% Phe: 0 0 0 0 0 9 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 25 0 9 9 9 0 9 9 0 % G
% His: 0 9 0 0 0 0 0 0 0 9 0 0 17 9 9 % H
% Ile: 17 9 17 0 42 0 0 17 0 0 17 0 0 0 9 % I
% Lys: 0 25 0 0 0 0 0 9 9 0 9 9 17 9 0 % K
% Leu: 0 9 0 0 0 0 9 9 9 9 42 9 9 0 17 % L
% Met: 0 0 9 9 0 9 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 9 0 0 50 0 9 0 9 17 9 0 25 9 % N
% Pro: 0 0 0 9 0 0 0 0 0 0 0 34 0 17 0 % P
% Gln: 0 9 0 25 17 9 9 0 0 9 0 0 17 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 9 0 0 9 9 0 9 34 9 0 0 17 9 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 17 0 50 0 17 9 0 0 50 9 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 9 0 0 34 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _