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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS7A
All Species:
27.27
Human Site:
S157
Identified Species:
42.86
UniProt:
Q9UBW8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBW8
NP_001157565.1
275
30277
S157
Q
R
L
E
V
D
Y
S
I
G
R
D
I
Q
R
Chimpanzee
Pan troglodytes
XP_001162737
248
27299
E134
Q
L
E
D
L
V
I
E
A
V
Y
A
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001108537
275
30301
S157
Q
R
L
E
V
D
Y
S
I
G
R
D
I
Q
R
Dog
Lupus familis
XP_543849
275
30288
S157
Q
R
L
E
V
D
Y
S
I
G
R
D
I
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ04
275
30206
S157
Q
R
L
E
V
D
Y
S
I
G
R
D
I
Q
R
Rat
Rattus norvegicus
NP_001157563
275
30201
S157
Q
R
L
E
V
D
Y
S
I
G
R
D
I
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518093
661
70489
S359
Q
R
L
E
V
D
Y
S
I
G
R
D
I
Q
R
Chicken
Gallus gallus
NP_001025946
275
30386
S157
Q
R
L
E
V
D
Y
S
I
G
R
D
I
R
R
Frog
Xenopus laevis
NP_001089653
264
29433
R148
I
Q
G
K
L
D
Q
R
N
Q
V
L
E
V
D
Zebra Danio
Brachydanio rerio
XP_697089
266
29243
R147
E
V
D
C
S
I
G
R
D
L
G
P
N
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4S8
278
31049
R158
G
K
L
F
Q
N
T
R
I
L
E
V
D
Y
A
Honey Bee
Apis mellifera
XP_395310
282
30757
G161
Q
L
E
V
D
Y
A
G
L
G
R
D
V
R
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785591
270
30197
V155
Q
K
N
Q
L
L
E
V
E
Y
T
I
G
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JU3
260
29450
D146
G
I
V
R
G
K
L
D
Q
L
K
R
C
F
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGS1
417
44522
A178
M
V
Q
I
N
S
V
A
A
L
R
D
V
P
A
Conservation
Percent
Protein Identity:
100
87.6
99.2
99.6
N.A.
98.9
98.9
N.A.
36.7
88.7
57
52
N.A.
40.6
43.6
N.A.
51.2
Protein Similarity:
100
88.3
100
99.6
N.A.
99.6
99.6
N.A.
39.7
94.5
76.3
68.3
N.A.
58.6
60.9
N.A.
70.1
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
93.3
6.6
0
N.A.
13.3
26.6
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
26.6
13.3
N.A.
26.6
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.8
N.A.
24.9
Protein Similarity:
N.A.
N.A.
N.A.
50.1
N.A.
40.5
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
7
14
0
0
7
0
0
14
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
7
7
7
54
0
7
7
0
0
60
14
0
14
% D
% Glu:
7
0
14
47
0
0
7
7
7
0
7
0
7
7
7
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
14
0
7
0
7
0
7
7
0
54
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
7
7
0
54
0
0
7
47
0
0
% I
% Lys:
0
14
0
7
0
7
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
14
54
0
20
7
7
0
7
27
0
7
0
0
14
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
7
0
0
7
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
7
% P
% Gln:
67
7
7
7
7
0
7
0
7
7
0
0
0
40
0
% Q
% Arg:
0
47
0
7
0
0
0
20
0
0
60
7
0
20
47
% R
% Ser:
0
0
0
0
7
7
0
47
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% T
% Val:
0
14
7
7
47
7
7
7
0
7
7
7
14
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
47
0
0
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _