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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BIN2 All Species: 10
Human Site: T279 Identified Species: 24.44
UniProt: Q9UBW5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBW5 NP_057377.2 565 61874 T279 S S P L T S P T S P S T L S L
Chimpanzee Pan troglodytes XP_509066 565 61637 T279 S S P L T S P T S P S T L S L
Rhesus Macaque Macaca mulatta XP_001088574 565 61717 T279 S S P L T S P T S P S T L S L
Dog Lupus familis XP_543665 497 54986 E224 A K T A K A E E E F N K A Q S
Cat Felis silvestris
Mouse Mus musculus O08539 588 64452 I311 S P A A T P E I R V N H E P E
Rat Rattus norvegicus Q68FR2 507 55100 V234 L N H S L Y E V M S K L E K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516791 687 75140 A275 S P L P S P A A S P N H T L A
Chicken Gallus gallus Q5ZKL7 476 51161 C203 L Y G S R I A C Y V T I F Q N
Frog Xenopus laevis NP_001085916 477 53519 G204 S L W N S R V G F Y V N T F Q
Zebra Danio Brachydanio rerio NP_956090 524 59262 S251 K K L E D Q H S T K P F I V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 90.9 65.1 N.A. 30.6 60.5 N.A. 34 48.8 38.5 41 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.4 93.8 70.2 N.A. 44.5 70.8 N.A. 51.9 59.4 52.3 56.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 13.3 0 N.A. 20 0 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 20 6.6 N.A. 33.3 6.6 13.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 20 0 10 20 10 0 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 30 10 10 0 0 0 20 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 10 0 10 10 10 0 % F
% Gly: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 10 0 0 0 0 20 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 10 0 0 0 10 10 0 0 % I
% Lys: 10 20 0 0 10 0 0 0 0 10 10 10 0 10 10 % K
% Leu: 20 10 20 30 10 0 0 0 0 0 0 10 30 10 30 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 0 0 0 0 0 30 10 0 0 10 % N
% Pro: 0 20 30 10 0 20 30 0 0 40 10 0 0 10 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 20 20 % Q
% Arg: 0 0 0 0 10 10 0 0 10 0 0 0 0 0 0 % R
% Ser: 60 30 0 20 20 30 0 10 40 10 30 0 0 30 10 % S
% Thr: 0 0 10 0 40 0 0 30 10 0 10 30 20 0 0 % T
% Val: 0 0 0 0 0 0 10 10 0 20 10 0 0 10 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 10 0 0 10 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _