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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BIN2
All Species:
13.33
Human Site:
S326
Identified Species:
32.59
UniProt:
Q9UBW5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBW5
NP_057377.2
565
61874
S326
E
E
I
E
K
E
G
S
E
A
S
S
S
E
E
Chimpanzee
Pan troglodytes
XP_509066
565
61637
S326
E
E
I
E
K
E
G
S
E
A
S
S
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001088574
565
61717
S326
E
E
I
E
K
E
G
S
E
A
S
S
S
E
E
Dog
Lupus familis
XP_543665
497
54986
Y270
S
N
L
R
D
V
F
Y
R
E
M
S
K
L
N
Cat
Felis silvestris
Mouse
Mus musculus
O08539
588
64452
E357
P
S
K
E
M
K
Q
E
Q
I
L
S
L
F
D
Rat
Rattus norvegicus
Q68FR2
507
55100
S280
S
P
V
S
P
V
T
S
P
T
S
P
N
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516791
687
75140
S333
D
N
F
V
P
E
I
S
V
T
T
P
S
Q
I
Chicken
Gallus gallus
Q5ZKL7
476
51161
G249
S
K
V
F
I
I
K
G
V
P
S
K
R
R
S
Frog
Xenopus laevis
NP_001085916
477
53519
S250
G
N
L
S
T
N
S
S
N
I
K
V
Q
P
R
Zebra Danio
Brachydanio rerio
NP_956090
524
59262
D297
M
S
K
L
S
M
P
D
T
L
A
H
T
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
90.9
65.1
N.A.
30.6
60.5
N.A.
34
48.8
38.5
41
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
93.8
70.2
N.A.
44.5
70.8
N.A.
51.9
59.4
52.3
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
13.3
13.3
N.A.
20
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
33.3
26.6
N.A.
40
20
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
30
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
10
0
0
0
0
0
10
10
% D
% Glu:
30
30
0
40
0
40
0
10
30
10
0
0
0
30
30
% E
% Phe:
0
0
10
10
0
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
30
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
30
0
10
10
10
0
0
20
0
0
0
0
10
% I
% Lys:
0
10
20
0
30
10
10
0
0
0
10
10
10
0
0
% K
% Leu:
0
0
20
10
0
0
0
0
0
10
10
0
10
10
10
% L
% Met:
10
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
30
0
0
0
10
0
0
10
0
0
0
10
0
10
% N
% Pro:
10
10
0
0
20
0
10
0
10
10
0
20
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% Q
% Arg:
0
0
0
10
0
0
0
0
10
0
0
0
10
10
10
% R
% Ser:
30
20
0
20
10
0
10
60
0
0
50
50
40
0
10
% S
% Thr:
0
0
0
0
10
0
10
0
10
20
10
0
10
0
10
% T
% Val:
0
0
20
10
0
20
0
0
20
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _