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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BIN2
All Species:
8.48
Human Site:
S263
Identified Species:
20.74
UniProt:
Q9UBW5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBW5
NP_057377.2
565
61874
S263
S
R
R
S
L
V
I
S
P
P
V
R
T
A
T
Chimpanzee
Pan troglodytes
XP_509066
565
61637
S263
S
R
R
S
L
V
I
S
P
P
V
Q
T
A
T
Rhesus Macaque
Macaca mulatta
XP_001088574
565
61717
S263
S
R
R
S
L
V
I
S
P
P
V
Q
T
T
M
Dog
Lupus familis
XP_543665
497
54986
V208
A
R
H
H
L
E
A
V
Q
N
A
K
K
K
D
Cat
Felis silvestris
Mouse
Mus musculus
O08539
588
64452
K295
N
A
P
E
K
G
N
K
S
P
S
P
P
P
D
Rat
Rattus norvegicus
Q68FR2
507
55100
D218
Q
N
I
S
N
L
R
D
V
F
Y
R
E
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516791
687
75140
K259
S
G
P
L
R
I
T
K
T
P
S
P
P
E
E
Chicken
Gallus gallus
Q5ZKL7
476
51161
R187
V
V
F
E
E
L
N
R
E
L
R
E
E
L
P
Frog
Xenopus laevis
NP_001085916
477
53519
N188
Q
K
V
F
E
E
M
N
V
D
L
Q
E
E
L
Zebra Danio
Brachydanio rerio
NP_956090
524
59262
L235
F
Y
K
E
M
S
M
L
N
H
N
I
Y
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
90.9
65.1
N.A.
30.6
60.5
N.A.
34
48.8
38.5
41
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
93.8
70.2
N.A.
44.5
70.8
N.A.
51.9
59.4
52.3
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
80
13.3
N.A.
6.6
13.3
N.A.
13.3
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
26.6
N.A.
13.3
26.6
N.A.
20
6.6
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
10
0
0
0
10
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
20
% D
% Glu:
0
0
0
30
20
20
0
0
10
0
0
10
30
20
10
% E
% Phe:
10
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
30
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
10
0
10
0
0
20
0
0
0
10
10
10
0
% K
% Leu:
0
0
0
10
40
20
0
10
0
10
10
0
0
10
10
% L
% Met:
0
0
0
0
10
0
20
0
0
0
0
0
0
10
20
% M
% Asn:
10
10
0
0
10
0
20
10
10
10
10
0
0
10
0
% N
% Pro:
0
0
20
0
0
0
0
0
30
50
0
20
20
10
10
% P
% Gln:
20
0
0
0
0
0
0
0
10
0
0
30
0
0
0
% Q
% Arg:
0
40
30
0
10
0
10
10
0
0
10
20
0
0
0
% R
% Ser:
40
0
0
40
0
10
0
30
10
0
20
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
0
10
0
0
0
30
10
20
% T
% Val:
10
10
10
0
0
30
0
10
20
0
30
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _