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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEL1L All Species: 26.67
Human Site: T610 Identified Species: 65.19
UniProt: Q9UBV2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBV2 NP_005056.3 794 88755 T610 S I V G E N E T Y P R A L L H
Chimpanzee Pan troglodytes XP_510102 773 86497 T589 T I V G E N E T Y P R A L L H
Rhesus Macaque Macaca mulatta XP_001105925 794 88622 T610 T I V G E N E T Y P R A L L H
Dog Lupus familis XP_537530 794 88678 T610 T I V G E N E T Y P R A L L H
Cat Felis silvestris
Mouse Mus musculus Q9Z2G6 790 88322 T606 T I V G E N E T Y P R A L L H
Rat Rattus norvegicus Q80Z70 794 88664 T610 T I V G E N E T Y P R A L L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505693 396 44201 G245 L G D Y H F Y G F G T D V D Y
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038629 776 85841 T593 Q I F N E N E T Y P R A L L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651179 819 89343 T606 Y Y G W G T S T D F E T A A A
Honey Bee Apis mellifera XP_392802 699 77656 R548 R A L A L W A R A A A Q G Y S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.2 98.9 97.7 N.A. 93 92.3 N.A. 47 N.A. N.A. 71.7 N.A. 43.8 48.6 N.A. N.A.
Protein Similarity: 100 97.3 99.3 98.4 N.A. 96.8 95.5 N.A. 48.4 N.A. N.A. 83.2 N.A. 60.4 62.9 N.A. N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 0 N.A. N.A. 80 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 N.A. N.A. 80 N.A. 6.6 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 10 0 10 10 10 70 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 10 0 0 10 0 10 0 % D
% Glu: 0 0 0 0 70 0 70 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 10 0 0 10 0 0 10 10 0 0 0 0 0 % F
% Gly: 0 10 10 60 10 0 0 10 0 10 0 0 10 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 70 % H
% Ile: 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 10 0 0 0 0 0 0 0 70 70 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 70 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 10 0 0 70 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % S
% Thr: 50 0 0 0 0 10 0 80 0 0 10 10 0 0 0 % T
% Val: 0 0 60 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 10 0 0 10 0 70 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _