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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSZ
All Species:
24.85
Human Site:
S115
Identified Species:
60.74
UniProt:
Q9UBR2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBR2
NP_001327.2
303
33868
S115
K
R
K
G
A
W
P
S
T
L
L
S
V
Q
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854795
375
41541
S187
K
R
K
G
A
W
P
S
T
L
L
S
V
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUU7
306
33978
S117
K
R
K
G
A
W
P
S
I
L
L
S
V
Q
N
Rat
Rattus norvegicus
Q9R1T3
306
34176
S117
K
R
K
G
A
W
P
S
T
L
L
S
V
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09648
218
23945
T31
S
C
W
A
F
S
T
T
G
A
L
E
G
Q
H
Frog
Xenopus laevis
NP_001088101
296
32990
S106
K
R
N
G
V
W
P
S
A
Y
L
S
V
Q
H
Zebra Danio
Brachydanio rerio
NP_001006043
301
33586
S107
K
R
K
A
A
W
P
S
A
Y
L
S
V
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
P179
F
G
C
N
G
G
D
P
L
A
A
W
R
Y
W
Sea Urchin
Strong. purpuratus
XP_788187
293
31563
S102
M
R
G
G
A
W
P
S
A
Y
L
S
V
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65493
355
39599
R144
L
P
K
S
V
D
W
R
K
K
G
A
V
A
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
67.7
N.A.
83
83.9
N.A.
N.A.
25
71.6
64
N.A.
N.A.
N.A.
23.4
56.1
Protein Similarity:
100
N.A.
N.A.
72.2
N.A.
89.5
90.1
N.A.
N.A.
38.2
79.8
76.5
N.A.
N.A.
N.A.
36.4
70.6
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
100
N.A.
N.A.
13.3
66.6
80
N.A.
N.A.
N.A.
0
73.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
N.A.
26.6
73.3
80
N.A.
N.A.
N.A.
0
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
60
0
0
0
30
20
10
10
0
10
0
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
60
10
10
0
0
10
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
60
0
60
0
0
0
0
0
10
10
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
10
40
80
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
10
0
0
0
0
70
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% Q
% Arg:
0
70
0
0
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
10
0
0
10
0
10
0
70
0
0
0
70
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
30
0
0
0
0
0
0
% T
% Val:
0
0
0
0
20
0
0
0
0
0
0
0
80
0
0
% V
% Trp:
0
0
10
0
0
70
10
0
0
0
0
10
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
30
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _