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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL1
All Species:
13.03
Human Site:
Y20
Identified Species:
19.11
UniProt:
Q9UBP6
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP6
NP_005362.3
276
31471
Y20
A
P
P
P
Q
K
R
Y
Y
R
Q
R
A
H
S
Chimpanzee
Pan troglodytes
XP_001167352
301
34100
Y45
A
P
P
P
Q
K
R
Y
Y
R
Q
R
A
H
S
Rhesus Macaque
Macaca mulatta
XP_001116496
301
34160
Y45
A
P
P
P
Q
K
R
Y
Y
R
Q
R
A
H
S
Dog
Lupus familis
XP_849422
247
28132
A20
E
L
Y
P
E
F
F
A
P
L
T
Q
N
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z120
268
30585
M24
Q
R
A
H
S
N
P
M
A
D
H
T
L
R
Y
Rat
Rattus norvegicus
XP_001054797
267
30550
M23
Q
R
A
H
S
N
P
M
A
D
H
T
L
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516298
226
25512
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU94
273
31824
Y22
V
T
L
P
Q
K
R
Y
Y
R
Q
R
A
H
S
Zebra Danio
Brachydanio rerio
Q5XJ57
241
27917
M20
Q
R
A
H
S
N
P
M
A
D
H
T
F
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77263
256
29406
N21
N
Q
E
P
D
V
L
N
P
T
S
A
V
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23126
256
30022
T20
D
H
K
P
T
C
E
T
V
P
G
L
P
Q
K
Sea Urchin
Strong. purpuratus
XP_790960
406
47124
I86
Q
K
K
V
R
E
A
I
N
A
K
S
S
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
B6SHG7
255
29101
R20
L
P
R
K
R
F
Y
R
A
R
A
H
S
N
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXB7
251
28800
F21
T
G
L
P
R
K
R
F
Y
R
A
R
A
H
S
Baker's Yeast
Sacchar. cerevisiae
Q12009
286
33373
E27
N
K
E
E
N
R
K
E
L
K
H
V
K
I
N
Red Bread Mold
Neurospora crassa
Q7RZC1
293
33715
F31
T
E
L
P
R
K
K
F
Y
R
Q
R
A
H
A
Conservation
Percent
Protein Identity:
100
90.6
90.6
81.5
N.A.
88
88.4
N.A.
64.8
N.A.
69.5
67.7
N.A.
47.4
N.A.
50.7
42.3
Protein Similarity:
100
91.3
91
83.6
N.A.
92.3
90.9
N.A.
72
N.A.
80
76.4
N.A.
59.7
N.A.
64.8
51.2
P-Site Identity:
100
100
100
6.6
N.A.
0
0
N.A.
0
N.A.
80
0
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
26.6
N.A.
0
0
N.A.
0
N.A.
80
0
N.A.
6.6
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
52.5
N.A.
50
46.8
48.8
Protein Similarity:
N.A.
68.4
N.A.
68.4
61.5
66.2
P-Site Identity:
N.A.
13.3
N.A.
60
0
53.3
P-Site Similarity:
N.A.
33.3
N.A.
73.3
26.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
19
0
0
0
7
7
25
7
13
7
38
0
13
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
0
0
0
19
0
0
0
0
0
% D
% Glu:
7
7
13
7
7
7
7
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
7
13
0
0
0
0
7
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
7
% G
% His:
0
7
0
19
0
0
0
0
0
0
25
7
0
38
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% I
% Lys:
0
13
13
7
0
38
13
0
0
7
7
0
7
7
7
% K
% Leu:
7
7
19
0
0
0
7
0
7
7
0
7
13
7
0
% L
% Met:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
7
19
0
7
7
0
0
0
7
7
7
% N
% Pro:
0
25
19
57
0
0
19
0
13
7
0
0
7
0
7
% P
% Gln:
25
7
0
0
25
0
0
0
0
0
32
7
0
13
0
% Q
% Arg:
0
19
7
0
25
7
32
7
0
44
0
38
0
13
0
% R
% Ser:
0
0
0
0
19
0
0
0
0
0
7
7
13
0
32
% S
% Thr:
13
7
0
0
7
0
0
7
0
7
7
19
0
7
7
% T
% Val:
7
0
0
7
0
7
0
0
7
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
7
25
38
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _