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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL1
All Species:
17.27
Human Site:
S226
Identified Species:
25.33
UniProt:
Q9UBP6
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP6
NP_005362.3
276
31471
S226
R
V
P
L
E
D
L
S
E
D
P
V
V
G
H
Chimpanzee
Pan troglodytes
XP_001167352
301
34100
S251
R
V
P
L
E
D
L
S
E
D
P
I
V
G
H
Rhesus Macaque
Macaca mulatta
XP_001116496
301
34160
S251
R
V
P
L
E
D
L
S
E
D
P
I
V
G
H
Dog
Lupus familis
XP_849422
247
28132
E205
H
L
G
T
S
T
E
E
G
K
K
V
L
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z120
268
30585
S220
R
V
P
L
E
E
L
S
E
D
P
I
V
E
H
Rat
Rattus norvegicus
XP_001054797
267
30550
S219
H
V
P
L
E
E
L
S
E
D
P
V
V
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516298
226
25512
K192
L
S
D
D
P
I
V
K
R
L
D
T
S
T
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU94
273
31824
V228
R
V
E
K
E
E
L
V
S
D
I
I
V
D
K
Zebra Danio
Brachydanio rerio
Q5XJ57
241
27917
I206
E
E
Q
L
A
D
D
I
I
V
G
H
L
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77263
256
29406
A222
E
R
L
T
E
E
E
A
N
A
D
P
I
T
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23126
256
30022
K218
R
L
T
E
E
E
M
K
K
D
P
I
V
E
M
Sea Urchin
Strong. purpuratus
XP_790960
406
47124
N364
R
L
S
D
E
E
M
N
M
D
P
I
V
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
B6SHG7
255
29101
K217
T
V
P
E
E
E
I
K
A
D
P
V
F
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXB7
251
28800
V214
S
L
T
Q
E
E
L
V
S
D
P
V
V
E
L
Baker's Yeast
Sacchar. cerevisiae
Q12009
286
33373
E247
R
L
S
K
E
W
E
E
N
D
E
C
V
K
I
Red Bread Mold
Neurospora crassa
Q7RZC1
293
33715
E249
R
V
S
V
E
E
Q
E
A
D
P
L
V
E
I
Conservation
Percent
Protein Identity:
100
90.6
90.6
81.5
N.A.
88
88.4
N.A.
64.8
N.A.
69.5
67.7
N.A.
47.4
N.A.
50.7
42.3
Protein Similarity:
100
91.3
91
83.6
N.A.
92.3
90.9
N.A.
72
N.A.
80
76.4
N.A.
59.7
N.A.
64.8
51.2
P-Site Identity:
100
93.3
93.3
6.6
N.A.
80
80
N.A.
0
N.A.
40
20
N.A.
6.6
N.A.
33.3
33.3
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
86.6
N.A.
6.6
N.A.
53.3
26.6
N.A.
26.6
N.A.
66.6
66.6
Percent
Protein Identity:
N.A.
52.5
N.A.
50
46.8
48.8
Protein Similarity:
N.A.
68.4
N.A.
68.4
61.5
66.2
P-Site Identity:
N.A.
40
N.A.
40
26.6
40
P-Site Similarity:
N.A.
53.3
N.A.
53.3
33.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
13
7
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
7
13
0
25
7
0
0
75
13
0
0
7
0
% D
% Glu:
13
7
7
13
82
57
19
19
32
0
7
0
0
32
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
7
0
7
0
0
25
0
% G
% His:
13
0
0
0
0
0
0
0
0
0
0
7
0
0
32
% H
% Ile:
0
0
0
0
0
7
7
7
7
0
7
38
7
0
13
% I
% Lys:
0
0
0
13
0
0
0
19
7
7
7
0
0
19
7
% K
% Leu:
7
32
7
38
0
0
44
0
0
7
0
7
13
0
13
% L
% Met:
0
0
0
0
0
0
13
0
7
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
7
13
0
0
0
0
0
7
% N
% Pro:
0
0
38
0
7
0
0
0
0
0
63
7
0
0
7
% P
% Gln:
0
0
7
7
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
57
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% R
% Ser:
7
7
19
0
7
0
0
32
13
0
0
0
7
0
0
% S
% Thr:
7
0
13
13
0
7
0
0
0
0
0
7
0
13
7
% T
% Val:
0
50
0
7
0
0
7
13
0
7
0
32
69
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _