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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPC4
All Species:
24.85
Human Site:
T691
Identified Species:
60.74
UniProt:
Q9UBN4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBN4
NP_001129427.1
977
112101
T691
R
K
P
E
S
F
G
T
I
G
R
R
A
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101078
974
111484
N695
D
G
R
R
R
R
R
N
L
R
S
F
T
E
R
Dog
Lupus familis
XP_543129
977
112324
T691
R
K
P
E
S
F
G
T
I
G
R
R
A
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUQ5
974
111557
T691
R
K
P
E
S
F
G
T
I
G
R
R
A
A
D
Rat
Rattus norvegicus
O35119
977
111829
T691
R
K
P
E
S
F
G
T
I
G
R
R
A
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511448
978
111652
T691
R
K
P
E
S
F
G
T
I
G
R
R
A
A
D
Chicken
Gallus gallus
XP_417089
974
111822
T690
R
K
P
E
S
F
G
T
I
G
R
R
A
A
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920781
915
105163
R639
D
I
E
W
K
F
A
R
T
K
L
W
M
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJJ7
1128
127091
T723
A
R
R
E
H
L
K
T
I
R
R
K
A
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34586
1027
118084
N731
Y
T
Y
Q
K
N
R
N
R
A
T
I
R
R
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
66.1
98.1
N.A.
97
97
N.A.
87.1
85
N.A.
72.7
N.A.
41.6
N.A.
34.6
N.A.
Protein Similarity:
100
N.A.
78.5
99
N.A.
98.1
98.4
N.A.
91.6
92
N.A.
83.6
N.A.
59.6
N.A.
55
N.A.
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
33.3
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
N.A.
46.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
10
0
0
70
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% D
% Glu:
0
0
10
70
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
70
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
10
0
0
0
0
60
0
0
60
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
70
0
0
10
0
0
0
% I
% Lys:
0
60
0
0
20
0
10
0
0
10
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
10
0
20
0
0
0
0
0
0
0
% N
% Pro:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
60
10
20
10
10
10
20
10
10
20
70
60
10
10
10
% R
% Ser:
0
0
0
0
60
0
0
0
0
0
10
0
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
70
10
0
10
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _