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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRPC4 All Species: 22.73
Human Site: S239 Identified Species: 55.56
UniProt: Q9UBN4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBN4 NP_001129427.1 977 112101 S239 K V E N E F K S E Y E E L S R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001101078 974 111484 A239 K V E N E F K A E Y E E L S Q
Dog Lupus familis XP_543129 977 112324 S239 K V E N E F K S E Y E E L S R
Cat Felis silvestris
Mouse Mus musculus Q9QUQ5 974 111557 S239 K V E N E F K S E Y E E L S R
Rat Rattus norvegicus O35119 977 111829 S239 K V E N E F K S E Y E E L S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511448 978 111652 S239 K V E N E F K S E Y E E L S R
Chicken Gallus gallus XP_417089 974 111822 S239 K V E N E F K S E Y E E L S R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920781 915 105163 L208 K A L A S P S L I A L S S E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJJ7 1128 127091 N229 F L E H E F K N E Y Q E L R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34586 1027 118084 E261 F E E H E F K E T Y L Q L S E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 66.1 98.1 N.A. 97 97 N.A. 87.1 85 N.A. 72.7 N.A. 41.6 N.A. 34.6 N.A.
Protein Similarity: 100 N.A. 78.5 99 N.A. 98.1 98.4 N.A. 91.6 92 N.A. 83.6 N.A. 59.6 N.A. 55 N.A.
P-Site Identity: 100 N.A. 86.6 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 N.A. 53.3 N.A. 46.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 N.A. 86.6 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 0 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 10 90 0 90 0 0 10 80 0 70 80 0 10 10 % E
% Phe: 20 0 0 0 0 90 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 80 0 0 0 0 0 90 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 10 0 0 0 0 10 0 0 20 0 90 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 70 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 60 % R
% Ser: 0 0 0 0 10 0 10 60 0 0 0 10 10 80 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 90 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _