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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASH2L
All Species:
28.18
Human Site:
Y268
Identified Species:
68.89
UniProt:
Q9UBL3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBL3
NP_001098684.1
628
68723
Y268
L
S
N
I
G
P
A
Y
D
N
Q
K
Q
S
S
Chimpanzee
Pan troglodytes
XP_001170172
628
68664
Y268
L
S
N
I
G
P
A
Y
D
N
Q
K
Q
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848878
628
68737
Y268
L
S
N
I
G
P
A
Y
D
N
Q
K
Q
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91X20
623
68232
Y263
L
S
N
I
G
P
A
Y
D
N
Q
K
Q
S
S
Rat
Rattus norvegicus
NP_001099559
623
68210
Y263
L
S
N
I
G
P
A
Y
D
N
Q
K
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519513
628
68515
Y268
L
G
N
I
G
P
A
Y
D
N
Q
K
Q
S
S
Chicken
Gallus gallus
NP_001026566
611
67054
Y251
L
A
N
I
G
P
A
Y
D
N
Q
K
Q
N
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103575
590
65997
S243
L
N
G
G
S
T
F
S
G
G
L
P
S
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397014
571
64707
E229
G
G
H
L
K
V
T
E
M
G
V
Q
H
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789737
791
88093
L428
K
L
G
S
S
L
K
L
D
S
S
Q
K
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
96.6
N.A.
95.8
95.2
N.A.
90.6
87
N.A.
77.3
N.A.
N.A.
43.7
N.A.
43.4
Protein Similarity:
100
99.6
N.A.
97.1
N.A.
96.6
96
N.A.
93.7
90.6
N.A.
85.8
N.A.
N.A.
58.5
N.A.
55.8
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
80
N.A.
6.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
100
N.A.
26.6
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
70
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
20
20
10
70
0
0
0
10
20
0
0
0
0
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
10
0
0
0
0
70
10
0
0
% K
% Leu:
80
10
0
10
0
10
0
10
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
70
0
0
0
0
0
0
70
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
70
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
70
20
70
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
50
0
10
20
0
0
10
0
10
10
0
10
60
70
% S
% Thr:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _