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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASH2L
All Species:
28.18
Human Site:
S280
Identified Species:
68.89
UniProt:
Q9UBL3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBL3
NP_001098684.1
628
68723
S280
Q
S
S
A
V
S
T
S
G
N
L
N
G
G
I
Chimpanzee
Pan troglodytes
XP_001170172
628
68664
S280
Q
S
S
A
V
S
T
S
G
N
L
N
G
G
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848878
628
68737
S280
Q
S
S
A
V
S
T
S
G
N
L
N
G
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91X20
623
68232
S275
Q
S
S
A
V
S
A
S
G
N
L
N
G
G
I
Rat
Rattus norvegicus
NP_001099559
623
68210
S275
Q
S
S
A
V
S
A
S
G
N
L
N
G
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519513
628
68515
S280
Q
S
S
A
V
S
T
S
G
N
L
N
G
G
I
Chicken
Gallus gallus
NP_001026566
611
67054
S263
Q
N
N
A
V
S
T
S
G
N
L
N
G
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103575
590
65997
R255
S
A
A
T
G
K
G
R
G
A
K
R
K
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397014
571
64707
N241
H
V
G
F
R
G
R
N
A
K
R
K
F
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789737
791
88093
S440
K
L
S
S
S
L
S
S
S
L
N
G
N
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
96.6
N.A.
95.8
95.2
N.A.
90.6
87
N.A.
77.3
N.A.
N.A.
43.7
N.A.
43.4
Protein Similarity:
100
99.6
N.A.
97.1
N.A.
96.6
96
N.A.
93.7
90.6
N.A.
85.8
N.A.
N.A.
58.5
N.A.
55.8
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
86.6
N.A.
6.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
100
N.A.
20
N.A.
N.A.
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
70
0
0
20
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
0
10
10
10
0
80
0
0
10
70
70
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% I
% Lys:
10
0
0
0
0
10
0
0
0
10
10
10
10
0
0
% K
% Leu:
0
10
0
0
0
10
0
0
0
10
70
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
10
0
70
10
70
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
70
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
0
0
0
10
0
10
10
0
0
10
10
0
0
0
% R
% Ser:
10
60
70
10
10
70
10
80
10
0
0
0
0
10
0
% S
% Thr:
0
0
0
10
0
0
50
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
70
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _